Literature DB >> 19957102

Synthesis and bioimmunological efficiency of poly(2-oxazolines) containing a free amino group.

J Kronek1, J Luston, Z Kroneková, E Paulovicová, P Farkas, N Petrencíková, L Paulovicová, I Janigová.   

Abstract

Novel amphiphilic copolymers on the basis of 2-oxazolines containing a free amino group were prepared. The copolymers were synthesized by the living cationic polymerization of 2-ethyl-2-oxazoline (ETOX) and 2-(4-aminophenyl)-2-oxazoline (APOX). The main goal of this work was the synthesis of water soluble polymer material with the defined number of functional groups necessary for the attachment of proteins and polysaccharides. A high concentration of free amino groups allows immobilization of various biosubstances, e.g. drugs, proteins or polysaccharides. Thermal properties have been studied with respect to the composition of the copolymers. Cytotoxicity and the bioimmunological efficiency of the selected copolymer were studied.

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Year:  2009        PMID： 19957102     DOI： 10.1007/s10856-009-3949-0

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN： 0957-4530            Impact factor:   3.896


  15 in total

1.  DNA transfection using linear poly(ethylenimine) prepared by controlled acid hydrolysis of poly(2-ethyl-2-oxazoline).

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Review 2.  Tissue repair and the dynamics of the extracellular matrix.

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3.  Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

Authors:  T Mosmann
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4.  Tetravinyl-tetramethylcyclo-tetrasiloxane (tetravinyl D4) is a mutagen in Rat2lambda lacI fibroblasts.

Authors:  K Felix; S Lin; G W Bornkamm; S Janz
Journal:  Carcinogenesis       Date:  1998-02       Impact factor: 4.944

5.  Enzymatic degradation of PLLA-PEOz-PLLA triblock copolymers.

Authors:  Chau-Hui Wang; Kuo-Rong Fan; Ging-Ho Hsiue
Journal:  Biomaterials       Date:  2005-06       Impact factor: 12.479

6.  Amphiphilic polymer supports for the asymmetric hydrogenation of amino acid precursors in water.

Authors:  M Tobias Zarka; Oskar Nuyken; Ralf Weberskirch
Journal:  Chemistry       Date:  2003-07-21       Impact factor: 5.236

7.  Preparation of synthetic polyoxazoline based carrier and Vibrio cholerae O-specific polysaccharide conjugate vaccine.

Authors:  Pavol Farkas; Jana Korcová; Juraj Kronek; Slavomír Bystrický
Journal:  Eur J Med Chem       Date:  2009-11-13       Impact factor: 6.514

Review 8.  Oxidative stress in phagocytes--"the enemy within".

Authors:  Wolf D Splettstoesser; Peter Schuff-Werner
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Review 9.  Poly(2-oxazolines) in biological and biomedical application contexts.

Authors:  Nico Adams; Ulrich S Schubert
Journal:  Adv Drug Deliv Rev       Date:  2007-08-22       Impact factor: 15.470

10.  Quantitation of epsilon-amino group using amino acids as reference standards by trinitrobenzene sulfonic acid. A simple spectrophotometric method for the estimation of hapten to carrier protein ratio.

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  6 in total

1.  In vitro study of partially hydrolyzed poly(2-ethyl-2-oxazolines) as materials for biomedical applications.

Authors:  Rushita Shah; Zuzana Kronekova; Anna Zahoranová; Ladislav Roller; Nabanita Saha; Petr Saha; Juraj Kronek
Journal:  J Mater Sci Mater Med       Date:  2015-03-18       Impact factor: 3.896

2.  In vitro bio-immunological and cytotoxicity studies of poly(2-oxazolines).

Authors:  Juraj Kronek; Zuzana Kroneková; Jozef Lustoň; Ema Paulovičová; Lucia Paulovičová; Barbara Mendrek
Journal:  J Mater Sci Mater Med       Date:  2011-05-22       Impact factor: 3.896

3.  Immunomodulatory efficiency of poly(2-oxazolines).

Authors:  Juraj Kronek; Ema Paulovičová; Lucia Paulovičová; Zuzana Kroneková; Jozef Lustoň
Journal:  J Mater Sci Mater Med       Date:  2012-03-29       Impact factor: 3.896

Review 4.  Poly(2-oxazoline)s as polymer therapeutics.

Authors:  Robert Luxenhofer; Yingchao Han; Anita Schulz; Jing Tong; Zhijian He; Alexander V Kabanov; Rainer Jordan
Journal:  Macromol Rapid Commun       Date:  2012-08-03       Impact factor: 5.734

5.  Processing of (Co)Poly(2-oxazoline)s by Electrospinning and Extrusion from Melt and the Postprocessing Properties of the (Co)Polymers.

Authors:  Wojciech Wałach; Natalia Oleszko-Torbus; Alicja Utrata-Wesołek; Marcelina Bochenek; Ewa Kijeńska-Gawrońska; Żaneta Górecka; Wojciech Święszkowski; Andrzej Dworak
Journal:  Polymers (Basel)       Date:  2020-02-02       Impact factor: 4.329

6.  Poly(2-oxazoline) Matrices with Temperature-Dependent Solubility-Interactions with Water and Use for Cell Culture.

Authors:  Natalia Oleszko-Torbus; Marcelina Bochenek; Alicja Utrata-Wesołek; Agnieszka Kowalczuk; Andrzej Marcinkowski; Andrzej Dworak; Agnieszka Fus-Kujawa; Aleksander L Sieroń; Wojciech Wałach
Journal:  Materials (Basel)       Date:  2020-06-13       Impact factor: 3.623
  6 in total

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