| Literature DB >> 19954947 |
Arion Kennedy1, Kristina Martinez, Soren Schmidt, Susanne Mandrup, Kathleen LaPoint, Michael McIntosh.
Abstract
Conjugated linoleic acid (CLA), a family of fatty acids found in beef, dairy foods and dietary supplements, reduces adiposity in several animal models of obesity and some human studies. However, the isomer-specific antiobesity mechanisms of action of CLA are unclear, and its use in humans is controversial. This review will summarize in vivo and in vitro findings from the literature regarding potential mechanisms by which CLA reduces adiposity, including its impact on (a) energy metabolism, (b) adipogenesis, (c) inflammation, (d) lipid metabolism and (e) apoptosis. 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2009 PMID： 19954947 PMCID： PMC2826589 DOI： 10.1016/j.jnutbio.2009.08.003
Source DB: PubMed Journal: J Nutr Biochem ISSN： 0955-2863 Impact factor: 6.048