BACKGROUND: The aim of this study was to perform an external validation of Cleveland Clinic Foundation colorectal cancer model in a single center. METHODS: Relevant data of 771 patients who underwent surgery for colorectal cancer between January 1997 and November 2008 were retrospectively collected. The performance of the scoring system was evaluated by discrimination and calibration. Discrimination was evaluated by using the area under the receiver operator characteristics curve and calibration by using the Hosmer-Lemeshow goodness-of-fit test. RESULTS: Mean age was 60.8 (18-91). Forty-four percent of patients were female, and 56% were male. Overall mortality was 3.9%. Cleveland Clinic Foundation colorectal cancer model showed good discrimination but poor calibration. CONCLUSION: These data suggest that the Cleveland Clinic Foundation colorectal cancer model is a suitable model to be used in our center for patients with colorectal cancer but requires recalibration.
BACKGROUND: The aim of this study was to perform an external validation of Cleveland Clinic Foundation colorectal cancer model in a single center. METHODS: Relevant data of 771 patients who underwent surgery for colorectal cancer between January 1997 and November 2008 were retrospectively collected. The performance of the scoring system was evaluated by discrimination and calibration. Discrimination was evaluated by using the area under the receiver operator characteristics curve and calibration by using the Hosmer-Lemeshow goodness-of-fit test. RESULTS: Mean age was 60.8 (18-91). Forty-four percent of patients were female, and 56% were male. Overall mortality was 3.9%. Cleveland Clinic Foundation colorectal cancer model showed good discrimination but poor calibration. CONCLUSION: These data suggest that the Cleveland Clinic Foundation colorectal cancer model is a suitable model to be used in our center for patients with colorectal cancer but requires recalibration.
Authors: P P Tekkis; D R Prytherch; H M Kocher; A Senapati; J D Poloniecki; J D Stamatakis; A C J Windsor Journal: Br J Surg Date: 2004-09 Impact factor: 6.939
Authors: Tamer Ertan; Omer Yoldas; Yusuf Alper Kilic; Mehmet Kilic; Erdal Göcmen; Mahmut Koc; Mesut Tez Journal: Am J Surg Date: 2008-04 Impact factor: 2.565
Authors: Samar Al-Homoud; Sanjay Purkayastha; Omer Aziz; Jason J Smith; Michael D Thompson; Ara W Darzi; Jeffrey D Stamatakis; Paris P Tekkis Journal: Surg Oncol Date: 2004 Aug-Nov Impact factor: 3.279