Mehul R Kamdar1, R Alex Gomez, Jeffrey A Ascherman. 1. New York, N.Y. From the Division of Plastic Surgery, Department of Surgery, New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, and Weill Cornell Medical College.
Abstract
BACKGROUND: Craniosynostosis alters the normal growth of the infant skull and can influence intracranial pressure and intracranial volume. The purpose of this study was to measure intracranial volumes in a large series of healthy children to serve as a reference for further studies exploring the impact of craniosynostosis and vault remodeling on intracranial growth. METHODS: A total of 123 children were included in this study from a retrospective review of pediatric emergency room visits for evaluation of head trauma where a head computed tomography scan was performed. Intracranial volumes were obtained using a semiautomated image segmentation technique and volume-rendering software. RESULTS: Volume measurements were obtained and plotted against age, and a best fit curve approximation was derived. In this study of healthy children, intracranial volume doubled by 9 months of age and tripled by 6 years of age. CONCLUSIONS: This large study contributes to the existing data demonstrating intracranial volumes in healthy children up to 6 years of age. These data can be used by clinicians as a reference in the assessment of a child presenting with cranial dysmorphology.
BACKGROUND:Craniosynostosis alters the normal growth of the infant skull and can influence intracranial pressure and intracranial volume. The purpose of this study was to measure intracranial volumes in a large series of healthy children to serve as a reference for further studies exploring the impact of craniosynostosis and vault remodeling on intracranial growth. METHODS: A total of 123 children were included in this study from a retrospective review of pediatric emergency room visits for evaluation of head trauma where a head computed tomography scan was performed. Intracranial volumes were obtained using a semiautomated image segmentation technique and volume-rendering software. RESULTS: Volume measurements were obtained and plotted against age, and a best fit curve approximation was derived. In this study of healthy children, intracranial volume doubled by 9 months of age and tripled by 6 years of age. CONCLUSIONS: This large study contributes to the existing data demonstrating intracranial volumes in healthy children up to 6 years of age. These data can be used by clinicians as a reference in the assessment of a child presenting with cranial dysmorphology.
Authors: Kirk Smith; David Politte; Gregory Reiker; Tracy S Nolan; Charles Hildebolt; Chelsea Mattson; Don Tucker; Fred Prior; Sergei Turovets; Linda J Larson-Prior Journal: Conf Proc IEEE Eng Med Biol Soc Date: 2013
Authors: James Cray; Jared Kneib; Lisa Vecchione; Craig Byron; Gregory M Cooper; Joseph E Losee; Michael I Siegel; Mark W Hamrick; James J Sciote; Mark P Mooney Journal: Anat Rec (Hoboken) Date: 2011-05-25 Impact factor: 2.064
Authors: Conor T Williams; David J Segar; Sybill D Naidoo; Gary B Skolnick; Mark R Proctor; Matthew D Smyth; Kamlesh B Patel Journal: J Craniofac Surg Date: 2019 Mar/Apr Impact factor: 1.046
Authors: Mary W Byrne; Jeffrey A Ascherman; Pasquale Casale; Robert A Cowles; Pamela F Gallin; Lynne G Maxwell Journal: J Neurosurg Anesthesiol Date: 2012-10 Impact factor: 3.956