Literature DB >> 19951353

Human telomeric G-quadruplex: structures of DNA and RNA sequences.

Anh Tuân Phan1.   

Abstract

Telomeres play an important role in cellular aging and cancer. Human telomeric DNA and RNA G-rich sequences are capable of forming a four-stranded structure, known as the G-quadruplex. Such a structure might be important for telomere biology and a good target for drug design. This minireview describes the structural diversity or conservation of DNA and RNA human telomeric G-quadruplexes, discusses structural views on targeting these G-quadruplexes and presents some future challenges for structural studies.

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Year:  2009        PMID： 19951353     DOI： 10.1111/j.1742-4658.2009.07464.x

Source DB:  PubMed          Journal:  FEBS J        ISSN： 1742-464X            Impact factor:   5.542


  117 in total

1.  Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents.

Authors:  Rupesh Nanjunda; Caterina Musetti; Arvind Kumar; Mohamed A Ismail; Abdelbasset A Farahat; Siming Wang; Claudia Sissi; Manlio Palumbo; David W Boykin; W David Wilson
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

2.  Effects of site-specific guanine C8-modifications on an intramolecular DNA G-quadruplex.

Authors:  Christopher Jacques Lech; Joefina Kim Cheow Lim; Jocelyn Mei Wen Lim; Samir Amrane; Brahim Heddi; Anh Tuân Phan
Journal:  Biophys J       Date:  2011-10-19       Impact factor: 4.033

Review 3.  A practical guide to studying G-quadruplex structures using single-molecule FRET.

Authors:  Parastoo Maleki; Jagat B Budhathoki; William A Roy; Hamza Balci
Journal:  Mol Genet Genomics       Date:  2017-02-01       Impact factor: 3.291

Review 4.  G4-associated human diseases.

Authors:  Nancy Maizels
Journal:  EMBO Rep       Date:  2015-07-06       Impact factor: 8.807

5.  Synthesis and biophysical analysis of modified thymine-containing DNA oligonucleotides.

Authors:  F Kawasaki; P Murat; Z Li; T Santner; S Balasubramanian
Journal:  Chem Commun (Camb)       Date:  2017-01-24       Impact factor: 6.222

6.  High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation.

Authors:  Abdelaziz Kerkour; Julien Marquevielle; Stefaniia Ivashchenko; Liliya A Yatsunyk; Jean-Louis Mergny; Gilmar F Salgado
Journal:  J Biol Chem       Date:  2017-03-22       Impact factor: 5.157

7.  Mass spectrometric studies on effects of counter ions of TMPyP4 on binding to human telomeric DNA and RNA G-quadruplexes.

Authors:  Li-Ping Bai; Jie Liu; Li Han; Hing-Man Ho; Renxiao Wang; Zhi-Hong Jiang
Journal:  Anal Bioanal Chem       Date:  2014-06-18       Impact factor: 4.142

8.  Thermodynamic characterization of human telomere quadruplex unfolding.

Authors:  R Buscaglia; R D Gray; J B Chaires
Journal:  Biopolymers       Date:  2013-12       Impact factor: 2.505

Review 9.  The long and the short of TRF2 in neurogenesis.

Authors:  Ioannis Grammatikakis; Peisu Zhang; Mark P Mattson; Myriam Gorospe
Journal:  Cell Cycle       Date:  2016-08-26       Impact factor: 4.534

10.  Synthesis of Macrocyclic Hexaoxazole (6OTD) Dimers, Containing Guanidine and Amine Functionalized Side Chains, and an Evaluation of Their Telomeric G4 Stabilizing Properties.

Authors:  Keisuke Iida; Masayuki Tera; Takatsugu Hirokawa; Kazuo Shin-Ya; Kazuo Nagasawa
Journal:  J Nucleic Acids       Date:  2010-05-24
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