Literature DB >> 19948139

Mitosis: too much of a good thing (can be bad).

Alexey Khodjakov1, Conly L Rieder.   

Abstract

Recent studies reveal that the precise regulation of microtubule dynamics is essential for an error-free mitosis. Kinetochore microtubule attachments that are too stable increase the rate of chromosome mis-segregation, a leading cause of chromosomal instability in tumors.

Entities:  

Mesh：

Year:  2009        PMID： 19948139      PMCID： PMC2891095          DOI： 10.1016/j.cub.2009.10.013

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  11 in total

1.  Kinetochores and microtubules in multipolar mitosis and chromosome orientation.

Authors:  W K Heneen
Journal:  Exp Cell Res       Date:  1975-03-01       Impact factor: 3.905

2.  Deviant kinetochore microtubule dynamics underlie chromosomal instability.

Authors:  Samuel F Bakhoum; Giulio Genovese; Duane A Compton
Journal:  Curr Biol       Date:  2009-10-29       Impact factor: 10.834

Review 3.  Beyond self-assembly: from microtubules to morphogenesis.

Authors:  M Kirschner; T Mitchison
Journal:  Cell       Date:  1986-05-09       Impact factor: 41.582

4.  Dynamic instability of microtubule growth.

Authors:  T Mitchison; M Kirschner
Journal:  Nature       Date:  1984 Nov 15-21       Impact factor: 49.962

5.  Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells.

Authors:  William T Silkworth; Isaac K Nardi; Lindsey M Scholl; Daniela Cimini
Journal:  PLoS One       Date:  2009-08-10       Impact factor: 3.240

Review 6.  Genetic instabilities in human cancers.

Authors:  C Lengauer; K W Kinzler; B Vogelstein
Journal:  Nature       Date:  1998-12-17       Impact factor: 49.962

7.  Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates.

Authors:  Dan Liu; Gerben Vader; Martijn J M Vromans; Michael A Lampson; Susanne M A Lens
Journal:  Science       Date:  2009-01-15       Impact factor: 47.728

8.  Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments.

Authors:  Zhenye Yang; Alison E Kenny; Daniela A Brito; Conly L Rieder
Journal:  J Cell Biol       Date:  2009-08-31       Impact factor: 10.539

9.  Genome stability is ensured by temporal control of kinetochore-microtubule dynamics.

Authors:  Samuel F Bakhoum; Sarah L Thompson; Amity L Manning; Duane A Compton
Journal:  Nat Cell Biol       Date:  2008-12-07       Impact factor: 28.824

10.  Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied.

Authors:  Daniela A Brito; Zhenye Yang; Conly L Rieder
Journal:  J Cell Biol       Date:  2008-08-18       Impact factor: 10.539
View more
  2 in total

Review 1.  Mitosis.

Authors:  J Richard McIntosh
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-09-01       Impact factor: 10.005

2.  Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division.

Authors:  Ihsan N Zulkipli; Sheba R David; Rajan Rajabalaya; Adi Idris
Journal:  Drug Target Insights       Date:  2015-06-15
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.