Literature DB >> 19942413

The echinocandins: three useful choices or three too many?

A M Bal1.   

Abstract

Echinocandins act by inhibiting 1,3-beta-D-glucan synthesis in the fungal cell wall. The three licensed agents in this class, namely anidulafungin, caspofungin and micafungin, have a favourable pharmacological profile. These agents are narrow spectrum with clinically relevant activity against Candida and Aspergillus spp. Several trials have established the non-inferiority of these agents over existing agents in the treatment of invasive fungal infections. Caspofungin is also licensed for empirical antifungal therapy of presumed fungal infections in patients with febrile neutropenia. This paper reviews the literature on echinocandins.

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Year:  2009        PMID: 19942413     DOI: 10.1016/j.ijantimicag.2009.09.011

Source DB:  PubMed          Journal:  Int J Antimicrob Agents        ISSN: 0924-8579            Impact factor:   5.283


  17 in total

1.  Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida and Aspergillus species.

Authors:  Elena De Carolis; Antonietta Vella; Ada R Florio; Patrizia Posteraro; David S Perlin; Maurizio Sanguinetti; Brunella Posteraro
Journal:  J Clin Microbiol       Date:  2012-04-25       Impact factor: 5.948

Review 2.  Echinocandin antifungal drugs in fungal infections: a comparison.

Authors:  Sharon C-A Chen; Monica A Slavin; Tania C Sorrell
Journal:  Drugs       Date:  2011-01-01       Impact factor: 9.546

3.  Novel carboline derivatives as potent antifungal lead compounds: design, synthesis, and biological evaluation.

Authors:  Shengzheng Wang; Yan Wang; Wei Liu; Na Liu; Yongqiang Zhang; Guoqiang Dong; Yang Liu; Zhengang Li; Xiaomeng He; Zhenyuan Miao; Jianzhong Yao; Jian Li; Wannian Zhang; Chunquan Sheng
Journal:  ACS Med Chem Lett       Date:  2014-02-13       Impact factor: 4.345

4.  Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization-time of flight mass spectrometry analysis.

Authors:  Antonietta Vella; Elena De Carolis; Luisa Vaccaro; Patrizia Posteraro; David S Perlin; Markus Kostrzewa; Brunella Posteraro; Maurizio Sanguinetti
Journal:  J Clin Microbiol       Date:  2013-07-03       Impact factor: 5.948

5.  Differential activities of three families of specific beta(1,3)glucan synthase inhibitors in wild-type and resistant strains of fission yeast.

Authors:  Ivone M Martins; Juan C G Cortés; Javier Muñoz; M Belén Moreno; Mariona Ramos; José A Clemente-Ramos; Angel Durán; Juan C Ribas
Journal:  J Biol Chem       Date:  2010-11-29       Impact factor: 5.157

6.  Comparison of the Etest and a rapid flow cytometry-based method with the reference CLSI broth microdilution protocol M27-A3 for the echinocandin susceptibility testing of Candida spp.

Authors:  L A Vale-Silva; P Pinto; V Lopes; H Ramos; E Pinto
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-09-10       Impact factor: 3.267

7.  Echinocandin antifungal drug resistance in Candida species: a cause for concern?

Authors:  Maurizio Sanguinetti; Patrizia Posteraro; Brunella Posteraro
Journal:  Curr Infect Dis Rep       Date:  2010-11       Impact factor: 3.725

8.  Caspofungin as secondary antifungal prophylaxis and subsequent maintenance antifungal prophylaxis therapy in hematological malignancy patients.

Authors:  Mingjuan Liu; Yan Li; Xiaoli Zhao; Yongqing Zhang; Bing Zhai; Qingyi Zhang; Lijun Wang; Yu Zhao; Honghua Li; Quanshun Wang; Chunji Gao; Wenrong Huang; Li Yu
Journal:  Int J Clin Exp Med       Date:  2015-07-15

9.  Pathogenesis and treatment of oral candidosis.

Authors:  David Williams; Michael Lewis
Journal:  J Oral Microbiol       Date:  2011-01-28       Impact factor: 5.474

10.  Susceptibility of clinical Candida species isolates to antifungal agents by E-test, Southern Iran: A five year study.

Authors:  P Badiee; A Alborzi
Journal:  Iran J Microbiol       Date:  2011-12
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