Literature DB >> 19940668

Dose reduction in computed tomographic angiography of pregnant patients with suspected acute pulmonary embolism.

Diana Litmanovich1, Phillip M Boiselle, Alexander A Bankier, Milliam L Kataoka, Oleg Pianykh, Vassilios Raptopoulos.   

Abstract

PURPOSE: The aim of this study was to quantify the effect of a reduced-dose pulmonary computed tomographic (CT) angiography protocol on radiation dose and image quality in pregnant patients as compared with a standard protocol.
MATERIALS AND METHODS: Twenty-six pregnant women with suspected pulmonary embolism underwent reduced-dose CT angiography (200 mA and 100 kV, from the aortic arch to the diaphragm). The matched control group standard protocol was 400 mA, 120 kilovolt (peak), and the entire thorax. The CT dose index, dose-length product, effective dose, image quality, and signal-to-noise ratio were assessed and compared with the Wilcoxon rank sum test result.
RESULTS: The CT dose index, mean dose-length product, and calculated effective dose were lower in the pregnancy group than in the controls: mean (SD), 5.21 (1.54) mGy versus 20.86 (5.59) mGy; 105.65 (39.77) mGy cm versus 575.71 (154.86) mGy cm, and 1.79 (0.676) msv versus 9.787 (2.63) msv, respectively (P < 0.0001). Quality scores of segmental (P = 0.266) and subsegmental (P = 0.207) arteries and arterial attenuation (P = 0.443) were similar.
CONCLUSIONS: In pregnant patients with suspected pulmonary embolism, combined reduction of kilovoltage and milliampere-second settings and z-axis coverage results in a substantial reduction of radiation dose while maintaining diagnostic imaging quality.

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Year:  2009        PMID: 19940668     DOI: 10.1097/RCT.0b013e318198cd18

Source DB:  PubMed          Journal:  J Comput Assist Tomogr        ISSN: 0363-8715            Impact factor:   1.826


  14 in total

Review 1.  Risks to the fetus from diagnostic imaging during pregnancy: review and proposal of a clinical protocol.

Authors:  Mafalda Gomes; Alexandra Matias; Filipe Macedo
Journal:  Pediatr Radiol       Date:  2015-08-14

2.  Outcomes of negative multidetector computed tomography with pulmonary angiography in pregnant women suspected of pulmonary embolism.

Authors:  Ghada Bourjeily; Hanan Khalil; Christina Raker; Susan Martin; Pauline Auger; Michel Chalhoub; Lucia Larson; Margaret Miller
Journal:  Lung       Date:  2011-10-18       Impact factor: 2.584

Review 3.  Imaging of Cardiovascular Disease in Pregnancy and the Peripartum Period.

Authors:  Theodore Pierce; Meline Hovnanian; Sandeep Hedgire; Brian Ghoshhajra
Journal:  Curr Treat Options Cardiovasc Med       Date:  2017-11-14

4.  CT pulmonary angiogram quality comparison between early and later pregnancy.

Authors:  Yoel Siegel; Russ Kuker; James Banks; Gary Danton
Journal:  Emerg Radiol       Date:  2017-05-04

Review 5.  The role of computed tomography in the diagnosis of acute and chronic pulmonary embolism.

Authors:  Halil Doğan; Albert de Roos; Jacob Geleijins; Menno V Huisman; Lucia J M Kroft
Journal:  Diagn Interv Radiol       Date:  2015 Jul-Aug       Impact factor: 2.630

6.  Reduced z-axis coverage in multidetector-row CT pulmonary angiography decreases radiation dose and diagnostic accuracy of alternative diseases.

Authors:  N Michalakis; C Keyzer; V De Maertelaer; D Tack; P A Gevenois
Journal:  Br J Radiol       Date:  2013-11-20       Impact factor: 3.039

7.  Image quality of low mA CT pulmonary angiography reconstructed with model based iterative reconstruction versus standard CT pulmonary angiography reconstructed with filtered back projection: an equivalency trial.

Authors:  Xavier Montet; Anne-Lise Hachulla; Angeliki Neroladaki; Frederic Lador; Thierry Rochat; Diomidis Botsikas; Christoph D Becker
Journal:  Eur Radiol       Date:  2014-12-21       Impact factor: 5.315

Review 8.  Imaging for the exclusion of pulmonary embolism in pregnancy.

Authors:  Thijs E van Mens; Luuk Jj Scheres; Paulien G de Jong; Mariska Mg Leeflang; Mathilde Nijkeuter; Saskia Middeldorp
Journal:  Cochrane Database Syst Rev       Date:  2017-01-26

9.  Reduced z-axis technique for CT Pulmonary angiography in pregnancy--validation for practical use and dose reduction.

Authors:  Kaushik Shahir; Jonathan M McCrea; Luis Antonio Sosa Lozano; Lawrence R Goodman
Journal:  Emerg Radiol       Date:  2015-08-25

10.  Imaging for suspected pulmonary embolism in pregnancy-what about the fetal dose? A comprehensive review of the literature.

Authors:  Tilo Niemann; Guillaume Nicolas; Hans W Roser; Jan Müller-Brand; Georg Bongartz
Journal:  Insights Imaging       Date:  2010-10-02
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