Literature DB >> 19936465

Experimental myocardium infarction in rats: analysis of the model.

Leonardo A M Zornoff1, Sergio A R Paiva, Marcos F Minicucci, Joel Spadaro.   

Abstract

One of the most often used strategies to study the physiopathological alterations caused by coronary occlusion is the use of the experimental infarction model in rats. Among other factors, this is due to the similarities in the physiopathological alterations that occur after the infarction in humans. One must consider, however, that this model has characteristics that can hinder the use as well as the interpretation of eventual outcomes. Thus, this review aims at analyzing the main characteristics of the experimental infarction model in rats, discussing the coronary occlusion technique, the consequences and the methods of morphological and functional assessment of the infarction and its clinical implications.

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Year:  2009        PMID: 19936465     DOI: 10.1590/s0066-782x2009001000018

Source DB:  PubMed          Journal:  Arq Bras Cardiol        ISSN: 0066-782X            Impact factor:   2.000


  27 in total

Review 1.  Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection.

Authors:  Hans Erik Bøtker; Derek Hausenloy; Ioanna Andreadou; Salvatore Antonucci; Kerstin Boengler; Sean M Davidson; Soni Deshwal; Yvan Devaux; Fabio Di Lisa; Moises Di Sante; Panagiotis Efentakis; Saveria Femminò; David García-Dorado; Zoltán Giricz; Borja Ibanez; Efstathios Iliodromitis; Nina Kaludercic; Petra Kleinbongard; Markus Neuhäuser; Michel Ovize; Pasquale Pagliaro; Michael Rahbek-Schmidt; Marisol Ruiz-Meana; Klaus-Dieter Schlüter; Rainer Schulz; Andreas Skyschally; Catherine Wilder; Derek M Yellon; Peter Ferdinandy; Gerd Heusch
Journal:  Basic Res Cardiol       Date:  2018-08-17       Impact factor: 17.165

2.  Histological Quantification of Chronic Myocardial Infarct in Rats.

Authors:  Jérémy Valentin; Aurélien Frobert; Guillaume Ajalbert; Stéphane Cook; Marie-Noëlle Giraud
Journal:  J Vis Exp       Date:  2016-12-11       Impact factor: 1.355

3.  Echocardiographic assessment of myocardial infarction: comparison of a rat model in two strains.

Authors:  R Esmaeili; A Sadeghpour; A Darbandi-Azar; K Majidzadeh-A; A Vajhi; M Sadeghizadeh
Journal:  Iran J Vet Res       Date:  2017       Impact factor: 1.376

4.  Variability in the cardiac venous system of Wistar rats.

Authors:  Lenka Krešáková; Halina Purzyc; Ingrid Schusterová; Benjamin Fulton; Marcela Maloveská; Katarina Vdoviaková; Zuzanna Kravcová; Martin Boldižár
Journal:  J Am Assoc Lab Anim Sci       Date:  2015-01       Impact factor: 1.232

5.  Preservation of Functional Microvascular Bed Is Vital for Long-Term Survival of Cardiac Myocytes Within Large Transmural Post-Myocardial Infarction Scar.

Authors:  Colleen Nofi; Yevgen Bogatyryov; Eduard I Dedkov
Journal:  J Histochem Cytochem       Date:  2017-11-08       Impact factor: 2.479

6.  Quantitation of acute necrosis after experimental myocardial infarction.

Authors:  Xin-Yi Yeap; Shirley Dehn; Jeremy Adelman; Jeremy Lipsitz; Edward B Thorp
Journal:  Methods Mol Biol       Date:  2013

7.  Association between Functional Variables and Heart Failure after Myocardial Infarction in Rats.

Authors:  Bertha F Polegato; Marcos F Minicucci; Paula S Azevedo; Andréa F Gonçalves; Aline F Lima; Paula F Martinez; Marina P Okoshi; Katashi Okoshi; Sergio A R Paiva; Leonardo A M Zornoff
Journal:  Arq Bras Cardiol       Date:  2016-01-26       Impact factor: 2.000

8.  Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial Infarction by Activating β-Arrestin-2, Protein Phosphatase 2A, and Glycogen Synthase Kinase-3 and Inhibiting β-Catenin.

Authors:  Refaat A Eid; Mohammad Adnan Khalil; Mahmoud A Alkhateeb; Samy M Eleawa; Mohamed Samir Ahmed Zaki; Attalla Farag El-Kott; Mubarak Al-Shraim; Fahmy El-Sayed; Muhammad Alaa Eldeen; Mashael Mohammed Bin-Meferij; Khalid M E Awaji; Abdullah S Shatoor
Journal:  Cardiovasc Drugs Ther       Date:  2021-12       Impact factor: 3.727

9.  Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy.

Authors:  Michael S Dodd; Helen J Atherton; Carolyn A Carr; Daniel J Stuckey; James A West; Julian L Griffin; George K Radda; Kieran Clarke; Lisa C Heather; Damian J Tyler
Journal:  Circ Cardiovasc Imaging       Date:  2014-09-08       Impact factor: 7.792

10.  Influence of Consumption of Orange Juice (Citrus Sinensis) on Cardiac Remodeling of Rats Submitted to Myocardial Infarction.

Authors:  Bruna C Oliveira; Priscila P Santos; Amanda M Figueiredo; Bruna P M Rafacho; Larissa Ishikawa; Silméia G Zanati; Ana A H Fernandes; Paula S Azevedo; Bertha F Polegato; Leonardo A M Zornoff; Marcos F Minicucci; Sergio A R Paiva
Journal:  Arq Bras Cardiol       Date:  2021-06       Impact factor: 2.000

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