Literature DB >> 19935241

Acellular dermal graft (AlloDerm) for upper eyelid reconstruction after cancer removal.

Brent Hayek1, Elham Hatef, Michael Nguyen, Viet Ho, Adam Hsu, Bita Esmaeli.   

Abstract

PURPOSE: To report the use of AlloDerm for reconstruction of large upper eyelid defects in cancer patients.
METHODS: The clinical records of all patients who had AlloDerm as part of their upper eyelid reconstruction between July 2005 and July 2006 at a single institution were reviewed. Functional and cosmetic outcomes and postoperative complications were assessed.
RESULTS: Two patients had recurrent sebaceous gland carcinoma, 2 had melanoma, and 1 had squamous cell carcinoma. The upper eyelid defect involved the full thickness and entire width of the upper eyelid in 4 patients and full thickness and two thirds of the upper eye eyelid in 1 patient. The reconstructive procedure included a modified Cutler-Beard procedure using AlloDerm as the posterior lamellar sandwich graft in all 5 patients. One patient had early postoperative adjuvant radiation therapy to the upper eyelid. Three patients had excellent functional and cosmetic outcome; 2 patients had satisfactory outcomes. Two patients had residual exposure keratopathy. Allergic reaction to AlloDerm, infectious transmission, and immunologic rejection were not encountered at the time of this report (mean follow-up time = 13 months).
CONCLUSIONS: AlloDerm can be used as an alternative sandwich graft material to replace the tarsus for reconstruction of large upper eyelid defects using a modified Cutler-Beard procedure.

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Year:  2009        PMID: 19935241     DOI: 10.1097/IOP.0b013e3181b78989

Source DB:  PubMed          Journal:  Ophthalmic Plast Reconstr Surg        ISSN: 0740-9303            Impact factor:   1.746


  6 in total

Review 1.  [Possibilities in the surgical management of eyelid trauma].

Authors:  K J Lipke
Journal:  HNO       Date:  2011-08       Impact factor: 1.284

Review 2.  Skin cancers and dermal substitutes: Is it safe? Review of the literature and presentation of a 2-stage surgical protocol for the treatment of non-melanoma skin cancers of the head in fragile patients.

Authors:  Marco Marcasciano; Marco Mazzocchi; Juste Kaciulyte; Noemi Spissu; Donato Casella; Diego Ribuffo; Luca Andrea Dessy
Journal:  Int Wound J       Date:  2018-06-04       Impact factor: 3.315

Review 3.  Advancements in the repair of large upper eyelid defects: A 10-year review.

Authors:  Erin Jennings; Mark Krakauer; William R Nunery; Vinay Kumar Aakalu
Journal:  Orbit       Date:  2020-09-29

4.  Total or subtotal replacement of tarsal plate by novel silicone plate for upper eyelid reconstruction in malignant tumors.

Authors:  Salil Kumar Mandal; Basupurna Majumdar; Purban Ganguly; Stephen C Dryden; James C Fleming; Brian T Fowler
Journal:  Indian J Ophthalmol       Date:  2021-10       Impact factor: 1.848

5.  Clinical observation on healing of tarsal plate defect after reconstruction with xenogeneic acellular dermal matrix.

Authors:  Qin Huang; Hongfei Liao; Yangbin Fang; Yaohua Wang
Journal:  BMC Ophthalmol       Date:  2022-07-29       Impact factor: 2.086

6.  Ovine forestomach matrix as a substrate for single-stage split-thickness graft reconstruction.

Authors:  Jeremy Simcock; Barnaby C H May
Journal:  Eplasty       Date:  2013-11-07
  6 in total

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