Literature DB >> 19934426

Acute-onset floaters and flashes: is this patient at risk for retinal detachment?

Hussein Hollands1, Davin Johnson, Anya C Brox, David Almeida, David L Simel, Sanjay Sharma.   

Abstract

CONTEXT: Acute onset of monocular floaters and/or flashes represents a common presentation to primary care physicians, and the most likely diagnosis is posterior vitreous detachment (PVD). A significant proportion of patients with acute PVD develop an associated retinal tear that can lead to retinal detachment and permanent vision loss if left untreated.
OBJECTIVE: To quantify the association between relevant clinical variables and risk of retinal tear in patients presenting with acute-onset floaters and/or flashes and PVD. DATA SOURCES: Structured MEDLINE (January 1950-September 2009) and EMBASE (January 1980-September 2009) searches and a hand search of references and citations of retrieved articles yielded 17 relevant studies. STUDY SELECTION: Studies of high-level methods that related elements of the history or physical examination in patients presenting with floaters and/or flashes and PVD to the likelihood of retinal tear.
RESULTS: For patients with acute onset of floaters and/or flashes who are self-referred or referred to an ophthalmologist, the prevalence of retinal tear is 14% (95% confidence interval [CI], 12%-16%). Subjective visual reduction is the most important symptom associated with retinal tear (likelihood ratio [LR], 5.0; 95% CI, 3.1-8.1). Vitreous hemorrhage on slitlamp biomicroscopy is the best-studied finding with the narrowest positive LR for retinal tear (summary LR, 10; 95% CI, 5.1-20). Absence of vitreous pigment during this examination is the best-studied finding with the narrowest negative LR (summary LR, 0.23; 95% CI, 0.12-0.43). Patients initially diagnosed as having uncomplicated PVD have a 3.4% chance of a retinal tear within 6 weeks. The risk increases with new onset of at least 10 floaters (summary LR, 8.1-36) or subjective visual reduction (summary LR, 2.3-17) during this period.
CONCLUSIONS: Primary care physicians should evaluate patients with acute-onset floaters and/or flashes due to suspected PVD, or patients with known PVD and a change in symptoms, for high-risk features of retinal tear and detachment. Physicians should always assess these patients' visual acuity. Patients at increased risk should be triaged for urgent ophthalmologic assessment.

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Mesh:

Year:  2009        PMID: 19934426     DOI: 10.1001/jama.2009.1714

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  23 in total

Review 1.  Acute-onset floaters and flashes.

Authors:  Davin Johnson; Hussein Hollands
Journal:  CMAJ       Date:  2011-11-28       Impact factor: 8.262

2.  Floater panic could cause overreferral.

Authors:  Ari Giligson
Journal:  CMAJ       Date:  2012-07-10       Impact factor: 8.262

3.  Risk factors for multiple retinal tears in patients with acute posterior vitreous detachment.

Authors:  Eyyup Karahan; Omer Karti; Duygu Er; Duygu Cam; Rukiye Aydın; Mehmet Ozgur Zengin; Suleyman Kaynak
Journal:  Int Ophthalmol       Date:  2017-02-03       Impact factor: 2.031

4.  Preservation of the structure of enzymatically-degraded bovine vitreous using synthetic proteoglycan mimics.

Authors:  Qianru Zhang; Benjamen A Filas; Robyn Roth; John Heuser; Nan Ma; Shaili Sharma; Alyssa Panitch; David C Beebe; Ying-Bo Shui
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-10-23       Impact factor: 4.799

5.  Oral fluoroquinolones and the incidence of rhegmatogenous retinal detachment and symptomatic retinal breaks: a population-based study.

Authors:  Kapil G Kapoor; David O Hodge; Jennifer L St Sauver; Andrew J Barkmeier
Journal:  Ophthalmology       Date:  2014-01-28       Impact factor: 12.079

6.  Unusual Manifestation of Choroidal Metastasis as Late Presentation of Treated Lung Cancer with Floaters.

Authors:  Mohamed Osman; Bashar Alwash; Ahmed Elkady; Sara Zeineldin
Journal:  Middle East Afr J Ophthalmol       Date:  2021-12-31

7.  A novel classification of high myopia into anterior and posterior pathologic subtypes.

Authors:  Cassie A Ludwig; Ryan A Shields; Tiffany A Chen; Matthew A Powers; D Wilkin Parke; Andrew A Moshfeghi; Darius M Moshfeghi
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-07-20       Impact factor: 3.117

8.  Validation of patient symptom diary in acute posterior vitreous detachment.

Authors:  Kelly D Schweitzer; Amaka A Eneh; Jonathan Hurst; Mark D Bona; Karim J Rahim; Marwan Abouammoh; Sanjay Sharma
Journal:  Saudi J Ophthalmol       Date:  2011-01-28

9.  Doctor-Shopping Behavior among Patients with Eye Floaters.

Authors:  Gow-Lieng Tseng; Cheng-Yu Chen
Journal:  Int J Environ Res Public Health       Date:  2015-07-13       Impact factor: 3.390

10.  Subjective signs of rhegmatogenous retinal detachment associated with acute posterior vitreous detachment.

Authors:  Ken-Ichi Sato; Shin-Ichi Nishimura
Journal:  J Clin Med Res       Date:  2013-04-23
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