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Literature DB >> 19923920

Epigenetic regulation of vertebrate Hox genes: a dynamic equilibrium.

Abstract

Temporal and spatial control of Hox gene expression is essential for correct patterning of many animals. In both Drosophila and vertebrates, Polycomb and Trithorax group complexes control the maintenance of Hox gene expression in appropriate domains. In vertebrates, dynamic changes in chromatin modifications are also observed during the sequential activation of Hox genes in the embryo, suggesting that progressive epigenetic modifications could regulate collinear gene activation.

Entities: Gene Species

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Year: 2009 PMID： 19923920 DOI： 10.4161/epi.4.8.10132

Source DB: PubMed Journal: Epigenetics ISSN： 1559-2294 Impact factor: 4.528

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Cited

28 in total

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