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Literature DB >> 19923581

The hedgehog pathway and pancreatic cancer.

Manuel Hidalgo¹, Anirban Maitra.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2009 PMID： 19923581 DOI： 10.1056/NEJMcibr0905857

Source DB: PubMed Journal: N Engl J Med ISSN： 0028-4793 Impact factor: 91.245

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Cited

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41 in total

1. Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer.

Authors: Sandra Baumgart; Elisabeth Glesel; Garima Singh; Nai-Ming Chen; Kristina Reutlinger; Jinsan Zhang; Daniel D Billadeau; Martin E Fernandez-Zapico; Thomas M Gress; Shiv K Singh; Volker Ellenrieder
Journal: Gastroenterology Date: 2011-11-10 Impact factor: 22.682

2. A piperidine chiron for the Veratrum alkaloids.

Authors: Douglass F Taber; Peter W DeMatteo
Journal: J Org Chem Date: 2012-04-13 Impact factor: 4.354

3. A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.

Authors: Venugopal Chenna; Chaoxin Hu; Dipankar Pramanik; Blake T Aftab; Collins Karikari; Nathaniel R Campbell; Seung-Mo Hong; Ming Zhao; Michelle A Rudek; Saeed R Khan; Charles M Rudin; Anirban Maitra
Journal: Mol Cancer Ther Date: 2011-10-25 Impact factor: 6.261

10. A Multi-institutional Phase 2 Study of Imatinib Mesylate and Gemcitabine for First-Line Treatment of Advanced Pancreatic Cancer.

Authors: Rebecca A Moss; Dirk Moore; Mary F Mulcahy; Kenneth Nahum; Biren Saraiya; Simantini Eddy; Martin Kleber; Elizabeth A Poplin
Journal: Gastrointest Cancer Res Date: 2012-05

The hedgehog pathway and pancreatic cancer.

1. Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer.

2. A piperidine chiron for the Veratrum alkaloids.

3. A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.

Review 4. Role of endoscopic ultrasound in the molecular diagnosis of pancreatic cancer.

Review 5. New targeted therapies in pancreatic cancer.

Review 6. New biomarkers and targets in pancreatic cancer and their application to treatment.

7. Emerging therapies in pancreas cancer.

8. Advanced pancreatic cancer: flourishing novel approaches in the era of biological therapy.

9. Gene expression profiling of the hedgehog signaling pathway in human meningiomas.

10. A Multi-institutional Phase 2 Study of Imatinib Mesylate and Gemcitabine for First-Line Treatment of Advanced Pancreatic Cancer.