Literature DB >> 19921591

In vitro cytotoxic and antioxidative activity of Cornus mas and Cotinus coggygria.

Katarina Savikin1, Gordana Zdunic, Teodora Jankovic, Tatjana Stanojkovic, Zorica Juranic, Nebojsa Menkovic.   

Abstract

Cytotoxicity and antioxidant properties of the methanol extracts of leaves and flowers of Cornus mas and Cotinus coggygria were studied, together with their chemical composition. Extracts of C. coggygria flowers and leaves showed better antioxidant activity in reaction with 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical as well as in inhibition of lipid peroxidation (LP) than C. mas extracts. Preliminary results showed that all extracts possessed potential cytotoxic activity towards HeLa and LS174 human cancer cell lines in vitro, with stronger inhibition against growth of HeLa cell growth than against LS174 cell growth. Cytotoxic activity of C. coggygria extracts showed good correlation with their antioxidative activity in vitro. In the brine shrimp lethality test, there were no significant changes in toxicity.

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Year:  2009        PMID： 19921591     DOI： 10.1080/14786410802267650

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  11 in total

1.  Cornelian Cherry (Cornus mas L.) Extracts Exert Cytotoxicity in Two Selected Melanoma Cell Lines-A Factorial Analysis of Time-Dependent Alterations in Values Obtained with SRB and MTT Assays.

Authors:  Łukasz Lewandowski; Iwona Bednarz-Misa; Alicja Z Kucharska; Agnieszka Kubiak; Patrycja Kasprzyk; Tomasz Sozański; Dominika Przybylska; Narcyz Piórecki; Małgorzata Krzystek-Korpacka
Journal:  Molecules       Date:  2022-06-29       Impact factor: 4.927

2.  Evaluation of Antioxidant and Antiproliferative Properties of Cornus mas L. Fruit Juice.

Authors:  Angeliki Tiptiri-Kourpeti; Eleni Fitsiou; Katerina Spyridopoulou; Stavros Vasileiadis; Christos Iliopoulos; Alex Galanis; Stavroula Vekiari; Aglaia Pappa; Katerina Chlichlia
Journal:  Antioxidants (Basel)       Date:  2019-09-05

Review 3.  Integrating Ethnobotany, Phytochemistry, and Pharmacology of Cotinus coggygria and Toxicodendron vernicifluum: What Predictions can be Made for the European Smoketree?

Authors:  Diana Simona Antal; Florina Ardelean; Robert Jijie; Iulia Pinzaru; Codruta Soica; Cristina Dehelean
Journal:  Front Pharmacol       Date:  2021-04-19       Impact factor: 5.810

4.  Preliminary Phytochemical Analysis and Evaluation of the Biological Activity of Leonotis nepetifolia (L.) R. Br Transformed Roots Extracts Obtained through Rhizobium rhizogenes-Mediated Transformation.

Authors:  Tomasz Kowalczyk; Anna Merecz-Sadowska; Patricia Rijo; Vera M S Isca; Laurent Picot; Marzena Wielanek; Tomasz Śliwiński; Przemysław Sitarek
Journal:  Cells       Date:  2021-05-18       Impact factor: 6.600

5.  Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria.

Authors:  Stanislav Sukhikh; Svetlana Noskova; Artem Pungin; Svetlana Ivanova; Liubov Skrypnik; Evgeny Chupakhin; Olga Babich
Journal:  Plants (Basel)       Date:  2021-06-16

6.  Effect and Mechanism of Total Flavonoids Extracted from Cotinus coggygria against Glioblastoma Cancer In Vitro and In Vivo.

Authors:  Gang Wang; JunJie Wang; Li Du; Fei Li
Journal:  Biomed Res Int       Date:  2015-10-18       Impact factor: 3.411

Review 7.  Cotinus coggygria Scop.: An overview of its chemical constituents, pharmacological and toxicological potential.

Authors:  Sanja Matić; Snežana Stanić; Mirjana Mihailović; Desanka Bogojević
Journal:  Saudi J Biol Sci       Date:  2015-05-22       Impact factor: 4.219

8.  Polyphenolic Profile and Targeted Bioactivity of Methanolic Extracts from Mediterranean Ethnomedicinal Plants on Human Cancer Cell Lines.

Authors:  Antonino Pollio; Armando Zarrelli; Valeria Romanucci; Alfredo Di Mauro; Federica Barra; Gabriele Pinto; Elvira Crescenzi; Emanuela Roscetto; Giuseppe Palumbo
Journal:  Molecules       Date:  2016-03-23       Impact factor: 4.411

9.  Protective effects of Cornus mas fruit extract on methotrexate-induced alterations in mice testicular tissue: Evidences for histochemical and histomorphometrical changes in an animal model study.

Authors:  Liela Zarei; Rasoul Shahrooz
Journal:  Vet Res Forum       Date:  2019-12-15       Impact factor: 1.054

10.  Protective effects of fisetin against myocardial ischemia/reperfusion injury.

Authors:  Lihui Long; Xuliang Han; Xingming Ma; Kai Li; Linjie Liu; Juanni Dong; Bei Qin; Kelin Zhang; Kuan Yang; Honglin Yan
Journal:  Exp Ther Med       Date:  2020-03-06       Impact factor: 2.447
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