Literature DB >> 19921013

Deazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylations.

Felipe E Zilly1, Andreas Taglieber, Frank Schulz, Frank Hollmann, Manfred T Reetz.   

Abstract

A light-driven deazaflavin-dependent direct enzyme regeneration system has been developed for a P450-BM3 catalyzed CH-activating hydroxylation, thereby avoiding the need for the expensive NADPH cofactor.

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Year:  2009        PMID： 19921013     DOI： 10.1039/b913863c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  12 in total

1.  Insights into an efficient light-driven hybrid P450 BM3 enzyme from crystallographic, spectroscopic and biochemical studies.

Authors:  Jessica Spradlin; Diana Lee; Sruthi Mahadevan; Mavish Mahomed; Lawrence Tang; Quan Lam; Alexander Colbert; Oliver S Shafaat; David Goodin; Marco Kloos; Mallory Kato; Lionel E Cheruzel
Journal:  Biochim Biophys Acta       Date:  2016-09-14

2.  Beyond the Protein Matrix: Probing Cofactor Variants in a Baeyer-Villiger Oxygenation Reaction.

Authors:  Christian Martinoli; Hanna M Dudek; Roberto Orru; Dale E Edmondson; Marco W Fraaije; Andrea Mattevi
Journal:  ACS Catal       Date:  2013       Impact factor: 13.084

Review 3.  Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications.

Authors:  Zhong Li; Yuanyuan Jiang; F Peter Guengerich; Li Ma; Shengying Li; Wei Zhang
Journal:  J Biol Chem       Date:  2019-12-06       Impact factor: 5.157

Review 4.  Keeping the spotlight on cytochrome P450.

Authors:  Hadil Shalan; Mallory Kato; Lionel Cheruzel
Journal:  Biochim Biophys Acta Proteins Proteom       Date:  2017-06-06       Impact factor: 3.036

5.  Light-initiated hydroxylation of lauric acid using hybrid P450 BM3 enzymes.

Authors:  Ngoc-Han Tran; Ngoc Huynh; Thuba Bui; Yen Nguyen; Phuong Huynh; Mary E Cooper; Lionel E Cheruzel
Journal:  Chem Commun (Camb)       Date:  2011-10-05       Impact factor: 6.222

6.  Bioelectronic delivery of electrons to cytochrome P450 enzymes.

Authors:  Sadagopan Krishnan; John B Schenkman; James F Rusling
Journal:  J Phys Chem B       Date:  2011-05-17       Impact factor: 2.991

7.  An efficient light-driven P450 BM3 biocatalyst.

Authors:  Ngoc-Han Tran; Daniel Nguyen; Sudharsan Dwaraknath; Sruthi Mahadevan; Garrett Chavez; Angelina Nguyen; Thanh Dao; Sarah Mullen; Thien-Anh Nguyen; Lionel E Cheruzel
Journal:  J Am Chem Soc       Date:  2013-09-19       Impact factor: 15.419

8.  Regio- and stereoselective hydroxylation of 10-undecenoic acid with a light-driven P450 BM3 biocatalyst yielding a valuable synthon for natural product synthesis.

Authors:  Mallory Kato; Daniel Nguyen; Melissa Gonzalez; Alejandro Cortez; Sarah E Mullen; Lionel E Cheruzel
Journal:  Bioorg Med Chem       Date:  2014-06-05       Impact factor: 3.641

9.  A series of hybrid P450 BM3 enzymes with different catalytic activity in the light-initiated hydroxylation of lauric acid.

Authors:  Ngoc-Han Tran; Ngoc Huynh; Garrett Chavez; Angelina Nguyen; Sudharsan Dwaraknath; Thien-Anh Nguyen; Maxine Nguyen; Lionel Cheruzel
Journal:  J Inorg Biochem       Date:  2012-06-02       Impact factor: 4.155

Review 10.  Ru(II)-diimine complexes and cytochrome P450 working hand-in-hand.

Authors:  Celine Eidenschenk; Lionel Cheruzel
Journal:  J Inorg Biochem       Date:  2020-09-12       Impact factor: 4.155
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