Literature DB >> 19920338

Human pancreatic islet progenitor cells demonstrate phenotypic plasticity in vitro.

Maithili P Dalvi1, Malati R Umrani, Mugdha V Joglekar, Anandwardhan A Hardikar.   

Abstract

Phenotypic plasticity is a phenomenon that describes the occurrence of 2 or more distinct phenotypes under diverse conditions. This article discusses the work carried out over the past few years in understanding the potential of human pancreatic islet-derived progenitors for cell replacement therapy in diabetes. The phenotypic plasticity exhibited by pancreatic progenitors during reversible epithelial-to-mesenchymal transition (EMT) and possible role of microRNAs in regulation of this process is also presented herein.

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Year:  2009        PMID: 19920338     DOI: 10.1007/s12038-009-0071-x

Source DB:  PubMed          Journal:  J Biosci        ISSN: 0250-5991            Impact factor:   1.826


  37 in total

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Journal:  Science       Date:  2001-04-26       Impact factor: 47.728

2.  Endocrine precursor cells from mouse islets are not generated by epithelial-to-mesenchymal transition of mature beta cells.

Authors:  Russell A Morton; Elizabeth Geras-Raaka; Leah M Wilson; Bruce M Raaka; Marvin C Gershengorn
Journal:  Mol Cell Endocrinol       Date:  2007-02-15       Impact factor: 4.102

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4.  DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells.

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Journal:  Oncogene       Date:  2005-03-31       Impact factor: 9.867

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Journal:  N Engl J Med       Date:  2006-09-28       Impact factor: 91.245

Review 6.  Teratocarcinomas and mammalian embryogenesis.

Authors:  G R Martin
Journal:  Science       Date:  1980-08-15       Impact factor: 47.728

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Authors:  Holger A Russ; Yael Bar; Philippe Ravassard; Shimon Efrat
Journal:  Diabetes       Date:  2008-03-03       Impact factor: 9.461

8.  Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis.

Authors:  Jing Yang; Sendurai A Mani; Joana Liu Donaher; Sridhar Ramaswamy; Raphael A Itzykson; Christophe Come; Pierre Savagner; Inna Gitelman; Andrea Richardson; Robert A Weinberg
Journal:  Cell       Date:  2004-06-25       Impact factor: 41.582

9.  Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates.

Authors:  Anandwardhan A Hardikar; Bernice Marcus-Samuels; Elizabeth Geras-Raaka; Bruce M Raaka; Marvin C Gershengorn
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-30       Impact factor: 11.205

10.  A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells.

Authors:  Ulrike Burk; Jörg Schubert; Ulrich Wellner; Otto Schmalhofer; Elizabeth Vincan; Simone Spaderna; Thomas Brabletz
Journal:  EMBO Rep       Date:  2008-05-16       Impact factor: 8.807

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  7 in total

1.  Cell culture models using rat primary alveolar type I cells.

Authors:  Charles A Downs; David W Montgomery; Carrie J Merkle
Journal:  Pulm Pharmacol Ther       Date:  2011-05-23       Impact factor: 3.410

2.  Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells.

Authors:  Zhan Shi; Ding Wu; Run Tang; Xiang Li; Renfu Chen; Song Xue; Chengjing Zhang; Xiaoqing Sun
Journal:  J Biosci       Date:  2016-06       Impact factor: 1.826

Review 3.  Extrinsic factors involved in the differentiation of stem cells into insulin-producing cells: an overview.

Authors:  Rebecca S Y Wong
Journal:  Exp Diabetes Res       Date:  2011-06-16

4.  Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo Study.

Authors:  Nidheesh Dadheech; Abhay Srivastava; Neha Paranjape; Shivika Gupta; Arpita Dave; Girish M Shah; Ramesh R Bhonde; Sarita Gupta
Journal:  PLoS One       Date:  2015-06-05       Impact factor: 3.240

5.  Coupled Feedback Loops Involving PAGE4, EMT and Notch Signaling Can Give Rise to Non-genetic Heterogeneity in Prostate Cancer Cells.

Authors:  Divyoj Singh; Federico Bocci; Prakash Kulkarni; Mohit Kumar Jolly
Journal:  Entropy (Basel)       Date:  2021-02-26       Impact factor: 2.524

6.  Evaluation of islets derived from human fetal pancreatic progenitor cells in diabetes treatment.

Authors:  Wen-Jian Zhang; Shi-Qing Xu; Han-Qing Cai; Xiu-Li Men; Zai Wang; Hua Lin; Li Chen; Yong-Wei Jiang; Hong-Lin Liu; Cheng-Hui Li; Wei-Guo Sui; Hong-Kui Deng; Jin-Ning Lou
Journal:  Stem Cell Res Ther       Date:  2013       Impact factor: 6.832

7.  Epigenetic and Transcriptome Profiling Identifies a Population of Visceral Adipose-Derived Progenitor Cells with the Potential to Differentiate into an Endocrine Pancreatic Lineage.

Authors:  Michael D Williams; Mugdha V Joglekar; Sarang N Satoor; Wilson Wong; Effie Keramidaris; Amanda Rixon; Philip O'Connell; Wayne J Hawthorne; Geraldine M Mitchell; Anandwardhan A Hardikar
Journal:  Cell Transplant       Date:  2018-10-30       Impact factor: 4.064

  7 in total

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