Literature DB >> 19919328

The role of anti-core antibody response in the detection of occult hepatitis B virus infection.

Simona Urbani1, Francesco Fagnoni, Gabriele Missale, Massimo Franchini.   

Abstract

Occult hepatitis B virus (HBV) infection is characterized by the presence of HBV DNA in serum and/or in the liver of patients negative for hepatitis B surface antigen (HBsAg). Occult infection may impact in several different clinical contexts including the risk of HBV transmission with transfusion or transplantation, and endogenous viral reactivation. The gold standard test for detection of occult infection is the amplification of HBV DNA. However, the serological assay for the long-lasting antibody response to the highly immunogenic HBV core antigen (anti-HBc) represents a qualified candidate as a surrogate for DNA amplification, or for increasing overall sensitivity when assessing the risk of occult hepatitis in peripheral blood. The risk of occult hepatitis associated with anti-HBc seropositivity has been demonstrated extensively, and the presence of antibody response to HBc can be considered a sentinel marker of occult HBV infection.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 19919328     DOI： 10.1515/CCLM.2010.002

Source DB:  PubMed          Journal:  Clin Chem Lab Med        ISSN： 1434-6621            Impact factor:   3.694


  24 in total

1.  Outcomes after hepatectomy of patients with positive HBcAb Non-B Non-C hepatocellular carcinoma compared to overt hepatitis B virus hepatocellular carcinoma.

Authors:  Shan-Shan Wu; Quan-Yuan Shan; Wen-Xuan Xie; Bin Chen; Yang Huang; Yu Guo; Xiao-Yan Xie; Ming-De Lu; Bao-Gang Peng; Ming Kuang; Shun-Li Shen; Wei Wang
Journal:  Clin Transl Oncol       Date:  2019-06-06       Impact factor: 3.405

Review 2.  Hepatitis B virus management to prevent reactivation after chemotherapy: a review.

Authors:  Jessica P Hwang; John M Vierling; Andrew D Zelenetz; Susan C Lackey; Rohit Loomba
Journal:  Support Care Cancer       Date:  2012-08-30       Impact factor: 3.603

3.  Serological pattern of Hepatitis B, C, and HIV infections among immigrants in Sicily: epidemiological aspects and implication on public health.

Authors:  Fabio Tramuto; Walter Mazzucco; Carmelo Massimo Maida; Andrea Affronti; Mario Affronti; Giuseppe Montalto; Francesco Vitale
Journal:  J Community Health       Date:  2012-06

4.  Impact of antibody to hepatitis B core antigen on the clinical course of hepatitis C virus carriers in a hyperendemic area in Japan: A community-based cohort study.

Authors:  Naoko Tsubouchi; Hirofumi Uto; Kotaro Kumagai; Fumisato Sasaki; Shuji Kanmura; Masatsugu Numata; Akihiro Moriuchi; Makoto Oketani; Akio Ido; Katsuhiro Hayashi; Kazunori Kusumoto; Kazuya Shimoda; Sherri O Stuver; Hirohito Tsubouchi
Journal:  Hepatol Res       Date:  2013-02-18       Impact factor: 4.288

Review 5.  Occult Hepatitis Infection in Transfusion Medicine: Screening Policy and Assessment of Current Use of Anti-HBc Testing.

Authors:  Antonella Esposito; Chiara Sabia; Carmela Iannone; Giovanni F Nicoletti; Linda Sommese; Claudio Napoli
Journal:  Transfus Med Hemother       Date:  2017-05-05       Impact factor: 3.747

6.  Occult hepatitis B infection in the immigrant population of Sicily, Italy.

Authors:  Fabio Tramuto; Carmelo M Maida; Giuseppina M E Colomba; Paola Di Carlo; Giovanni Mazzola; Valentina Li Vecchi; Mario Affronti; Giuseppe Montalto; Francesco Vitale
Journal:  J Immigr Minor Health       Date:  2013-08

7.  Detection of occult hepatitis B and window period infection among blood donors by individual donation nucleic acid testing in a tertiary care center in South India.

Authors:  Cinzia S Keechilot; Veena Shenoy; Anil Kumar; Lalitha Biswas; Sukhithasri Vijayrajratnam; Kavitha Dinesh; Prem Nair
Journal:  Pathog Glob Health       Date:  2016-10-27       Impact factor: 2.894

Review 8.  Occult hepatitis B virus infection.

Authors:  Min-Sun Kwak; Yoon Jun Kim
Journal:  World J Hepatol       Date:  2014-12-27

Review 9.  Diagnostic strategy for occult hepatitis B virus infection.

Authors:  Sara Ocana; Maria Luisa Casas; Ingrid Buhigas; Jose Luis Lledo
Journal:  World J Gastroenterol       Date:  2011-03-28       Impact factor: 5.742

Review 10.  Occult HBV infection in the oncohematological setting.

Authors:  C Sagnelli; M Macera; M Pisaturo; R Zampino; M Coppola; E Sagnelli
Journal:  Infection       Date:  2016-04-13       Impact factor: 3.553
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.