Literature DB >> 19919132

Enzyme responsive nanocontainers with cyclodextrin gatekeepers and synergistic effects in release of guests.

Chiyoung Park1, Hyehyeon Kim, Saehee Kim, Chulhee Kim.   

Abstract

The cyclodextrin covered porous silica nanoparticles (Si-MPs) exhibited enzyme responsive characteristics. The cyclodextrin gatekeepers on the surface of Si-MPs can be hydrolyzed by a-amylase to release guest molecules from the porous reservoir. The ester linkage in the stalk part of the cyclodextrin gatekeeper can also be cleaved by lipase to release guests from the channel. Our approach would provide a unique methodology for controlled delivery systems.

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Year:  2009        PMID： 19919132     DOI： 10.1021/ja9061085

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  26 in total

Review 1.  Mechanized silica nanoparticles: a new frontier in theranostic nanomedicine.

Authors:  Michael W Ambrogio; Courtney R Thomas; Yan-Li Zhao; Jeffrey I Zink; J Fraser Stoddart
Journal:  Acc Chem Res       Date:  2011-06-15       Impact factor: 22.384

2.  DNA-capped mesoporous silica nanoparticles as an ion-responsive release system to determine the presence of mercury in aqueous solutions.

Authors:  Yunfei Zhang; Quan Yuan; Tao Chen; Xiaobing Zhang; Yan Chen; Weihong Tan
Journal:  Anal Chem       Date:  2012-01-30       Impact factor: 6.986

3.  Supramolecular host-guest interaction for labeling and detection of cellular biomarkers.

Authors:  Sarit S Agasti; Monty Liong; Carlos Tassa; Hyun Jung Chung; Stanley Y Shaw; Hakho Lee; Ralph Weissleder
Journal:  Angew Chem Int Ed Engl       Date:  2011-11-24       Impact factor: 15.336

4.  Photon-manipulated drug release from a mesoporous nanocontainer controlled by azobenzene-modified nucleic acid.

Authors:  Quan Yuan; Yunfei Zhang; Tao Chen; Danqing Lu; Zilong Zhao; Xiaobing Zhang; Zhenxing Li; Chun-Hua Yan; Weihong Tan
Journal:  ACS Nano       Date:  2012-06-18       Impact factor: 15.881

Review 5.  Nanoplatforms for Targeted Stimuli-Responsive Drug Delivery: A Review of Platform Materials and Stimuli-Responsive Release and Targeting Mechanisms.

Authors:  Yuzhe Sun; Edward Davis
Journal:  Nanomaterials (Basel)       Date:  2021-03-16       Impact factor: 5.076

6.  Versatile fluorescence resonance energy transfer-based mesoporous silica nanoparticles for real-time monitoring of drug release.

Authors:  Jinping Lai; Birju P Shah; Eric Garfunkel; Ki-Bum Lee
Journal:  ACS Nano       Date:  2013-03-11       Impact factor: 15.881

7.  Photoexpulsion of surface-grafted ruthenium complexes and subsequent release of cytotoxic cargos to cancer cells from mesoporous silica nanoparticles.

Authors:  Marco Frasconi; Zhichang Liu; Juying Lei; Yilei Wu; Elena Strekalova; Dmitry Malin; Michael W Ambrogio; Xinqi Chen; Youssry Y Botros; Vincent L Cryns; Jean-Pierre Sauvage; J Fraser Stoddart
Journal:  J Am Chem Soc       Date:  2013-07-25       Impact factor: 15.419

8.  Measurement of Uptake and Release Capacities of Mesoporous Silica Nanoparticles Enabled by Nanovalve Gates.

Authors:  Zongxi Li; Jeff Nyalosaso Likoko; Angela A Hwang; Daniel P Ferris; Sui Yang; Gaelle Derrien; Clarence Charnay; Jean-Olivier Durand; Jeffrey I Zink
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2011-10-13       Impact factor: 4.126

9.  Liposome-coated mesoporous silica nanoparticles loaded with L-cysteine for photoelectrochemical immunoassay of aflatoxin B1.

Authors:  Youxiu Lin; Qian Zhou; Yongyi Zeng; Dianping Tang
Journal:  Mikrochim Acta       Date:  2018-06-02       Impact factor: 5.833

10.  Ultrasound responsive mesoporous silica nanoparticles for biomedical applications.

Authors:  Miguel Manzano; María Vallet-Regí
Journal:  Chem Commun (Camb)       Date:  2019-02-28       Impact factor: 6.222
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