Literature DB >> 1991508

Thimerosal causes calcium oscillations and sensitizes calcium-induced calcium release in unfertilized hamster eggs.

K Swann1.   

Abstract

Calcium-induced-calcium-release (CICR) was assayed in unfertilized golden hamster eggs by injecting Ca2+ and monitoring Ca2(+)-dependent hyperpolarizing responses (HRs) and Ca2(+)-sensitive fluo-3 fluorescence. Incubating eggs in the sulfhydryl reagent thimerosal caused [Ca2+]i oscillations as monitored by Ca2(+)-dependent HRs and decreased approximately 10-fold the Ca2+ injection current required to generate an HR and cause a large intracellular Ca2+ increase. Thimerosal also enhanced the sensitivity of eggs to Ca2+ injection in a calcium-free medium. The effects of thimerosal on CICR were prevented by dithiothreitol and were not mimicked by injecting inositol 1,4,5-trisphosphate. The data suggest that thimerosal may be an alternative agent for studying CICR in caffeine-insensitive cells.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1991508     DOI： 10.1016/0014-5793(91)80110-o

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  14 in total

1.  Luminal Ca2+ promoting spontaneous Ca2+ release from inositol trisphosphate-sensitive stores in rat hepatocytes.

Authors:  L Missiaen; C W Taylor; M J Berridge
Journal:  J Physiol       Date:  1992-09       Impact factor: 5.182

2.  Regulation of endoplasmic reticulum Ca(2+) oscillations in mammalian eggs.

Authors:  Takuya Wakai; Nan Zhang; Peter Vangheluwe; Rafael A Fissore
Journal:  J Cell Sci       Date:  2013-10-07       Impact factor: 5.285

Review 3.  Regulatory Mechanisms of Endoplasmic Reticulum Resident IP3 Receptors.

Authors:  Syed Zahid Ali Shah; Deming Zhao; Sher Hayat Khan; Lifeng Yang
Journal:  J Mol Neurosci       Date:  2015-04-10       Impact factor: 3.444

4.  Transactivation of the epidermal growth factor receptor by heat shock protein 90 via Toll-like receptor 4 contributes to the migration of glioblastoma cells.

Authors:  Dominique Thuringer; Arlette Hammann; Naïma Benikhlef; Eric Fourmaux; André Bouchot; Guillaume Wettstein; Eric Solary; Carmen Garrido
Journal:  J Biol Chem       Date:  2010-12-02       Impact factor: 5.157

5.  Thiol oxidation by 2,2'-dithiodipyridine causes a reversible increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells. Role for inositol 1,4,5-trisphosphate-sensitive Ca2+ stores.

Authors:  M S Islam; H Kindmark; O Larsson; P O Berggren
Journal:  Biochem J       Date:  1997-01-15       Impact factor: 3.857

6.  Cytosolic Ca2+ spikes evoked by the thiol reagent thimerosal in both intact and internally perfused single pancreatic acinar cells.

Authors:  P Thorn; P Brady; J Llopis; D V Gallacher; O H Petersen
Journal:  Pflugers Arch       Date:  1992-11       Impact factor: 3.657

7.  Bell-shaped activation of inositol-1,4,5-trisphosphate-induced Ca2+ release by thimerosal in permeabilized A7r5 smooth-muscle cells.

Authors:  J B Parys; L Missiaen; H De Smedt; G Droogmans; R Casteels
Journal:  Pflugers Arch       Date:  1993-09       Impact factor: 3.657

8.  Reversible blockade of the calcium-activated nonselective cation channel in brown fat cells by the sulfhydryl reagents mercury and thimerosal.

Authors:  A Koivisto; D Siemen; J Nedergaard
Journal:  Pflugers Arch       Date:  1993-12       Impact factor: 3.657

9.  Different triggers for calcium oscillations in mouse eggs involve a ryanodine-sensitive calcium store.

Authors:  K Swann
Journal:  Biochem J       Date:  1992-10-01       Impact factor: 3.857

10.  Analysis of cat oocyte activation methods for the generation of feline disease models by nuclear transfer.

Authors:  Chunmin Wang; William F Swanson; Jason R Herrick; Kiho Lee; Zoltan Machaty
Journal:  Reprod Biol Endocrinol       Date:  2009-12-11       Impact factor: 5.211
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.