Literature DB >> 19913003

The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department.

Peter A Kavsak1, Alice M Newman, Dennis T Ko, Andrew R Macrae, Allan S Jaffe.   

Abstract

OBJECTIVE: To determine if a cytokine panel could be informative regarding subsequent heart failure(HF)/death. DESIGN AND METHODS: In 216 subjects presenting with chest pain to an emergency department in 1996, EDTA plasma (-70 degrees C) was thawed for IL-6, MCP-1, IL-10, VEGF, EGF measurement.
RESULTS: Subjects with any three cytokines elevated were at higher risk for HF/death compared to those with < or = two cytokines elevated. DISCUSSION: A cytokine panel might be useful for risk stratification for HF/death. Copyright 2009 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

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Year:  2009        PMID: 19913003      PMCID: PMC3569498          DOI: 10.1016/j.clinbiochem.2009.11.004

Source DB:  PubMed          Journal:  Clin Biochem        ISSN: 0009-9120            Impact factor:   3.281


  10 in total

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