Literature DB >> 19902952

A selenide-based approach to photochemical cleavage of peptide and protein backbones at engineered backbone esters.

Amy L Eastwood1, Angela P Blum, Niki M Zacharias, Dennis A Dougherty.   

Abstract

A strategy for photochemical cleavage of peptide and protein backbones is described, which is based on a selenide-mediated cleavage of a backbone ester moiety. Studies in model systems establish the viability of the chemistry and suggest the method could be a valuable tool for chemical biology studies of proteins.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19902952      PMCID： PMC2953381          DOI： 10.1021/jo901368g

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  18 in total

1.  Mapping disulfide connectivity using backbone ester hydrolysis.

Authors:  P M England; H A Lester; D A Dougherty
Journal:  Biochemistry       Date:  1999-10-26       Impact factor: 3.162

2.  Design and synthesis of photochemically controllable caspase-3.

Authors:  Masayuki Endo; Koji Nakayama; Yuka Kaida; Tetsuro Majima
Journal:  Angew Chem Int Ed Engl       Date:  2004-10-25       Impact factor: 15.336

3.  A ligation and photorelease strategy for the temporal and spatial control of protein function in living cells.

Authors:  Jean-Philippe Pellois; Tom W Muir
Journal:  Angew Chem Int Ed Engl       Date:  2005-09-05       Impact factor: 15.336

4.  Control of the yeast cell cycle with a photocleavable alpha-factor analogue.

Authors:  Laurie L Parker; Josh W Kurutz; Stephen B H Kent; Stephen J Kron
Journal:  Angew Chem Int Ed Engl       Date:  2006-09-25       Impact factor: 15.336

5.  Synthesis of a stimulus-responsive processing device and its application to a nucleocytoplasmic shuttle Peptide.

Authors:  Akira Shigenaga; Daisuke Tsuji; Naomi Nishioka; Shugo Tsuda; Kohji Itoh; Akira Otaka
Journal:  Chembiochem       Date:  2007-11-05       Impact factor: 3.164

6.  Ribosome-catalyzed polyester formation.

Authors:  S Fahnestock; A Rich
Journal:  Science       Date:  1971-07-23       Impact factor: 47.728

7.  Site-specific, photochemical proteolysis applied to ion channels in vivo.

Authors:  P M England; H A Lester; N Davidson; D A Dougherty
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-30       Impact factor: 11.205

8.  Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.

Authors:  P M England; Y Zhang; D A Dougherty; H A Lester
Journal:  Cell       Date:  1999-01-08       Impact factor: 41.582

9.  Factors controlling photochemical cleavage of the energetically unfavorable Ph-Se bond of alkyl phenyl selenides.

Authors:  Akihiko Ouchi; Suyou Liu; Zhong Li; S Ajaya Kumar; Toshiaki Suzuki; Takeshi Hyugano; Haruo Kitahara
Journal:  J Org Chem       Date:  2007-10-16       Impact factor: 4.354

10.  Probing backbone hydrogen bonds in the hydrophobic core of GCN4.

Authors:  John W Blankenship; Rema Balambika; Philip E Dawson
Journal:  Biochemistry       Date:  2002-12-31       Impact factor: 3.162
View more
  2 in total

1.  Stimuli Induced Uptake of Protein-Like Peptide Brush Polymers.

Authors:  Angela P Blum; Jian Yin; Helen H Lin; Blayne A Oliver; Jacquelin K Kammeyer; Matthew P Thompson; Michael K Gilson; Nathan C Gianneschi
Journal:  Chemistry       Date:  2021-12-16       Impact factor: 5.236

Review 2.  In vivo incorporation of non-canonical amino acids by using the chemical aminoacylation strategy: a broadly applicable mechanistic tool.

Authors:  Dennis A Dougherty; Ethan B Van Arnam
Journal:  Chembiochem       Date:  2014-07-02       Impact factor: 3.164
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.