Literature DB >> 19897169

Simultaneous bilateral Achilles tendon ruptures associated with statin medication despite regular rock climbing exercise.

Michael R Carmont1, Adrian M Highland, Christopher M Blundell, Mark B Davies.   

Abstract

INTRODUCTION: Ruptures of the Achilles tendon are common however simultaneous ruptures occur less frequently. Eccentric loading exercise programmes have been used to successfully treat Achilles tendinopathy. CASE REPORT: We report a case of simultaneous bilateral Achilles tendon rupture in a patient predisposed to rupture due to longstanding raised serum lipoprotein and recently introduced therapeutic statin medication. The patient was also a keen rock climber and had regularly undertaken loading exercise.
CONCLUSION: This case illustrates that the therapeutic effect of mixed loading exercises for the Achilles tendon may not be adequate to overcome the predisposition to rupture caused by hyperlipidaemia and statin medication.

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Year:  2009        PMID: 19897169     DOI: 10.1016/j.ptsp.2009.01.003

Source DB:  PubMed          Journal:  Phys Ther Sport        ISSN: 1466-853X            Impact factor:   2.365


  5 in total

1.  Statin-induced calcific Achilles tendinopathy in rats: comparison of biomechanical and histopathological effects of simvastatin, atorvastatin and rosuvastatin.

Authors:  Ferda Kaleağasıoğlu; Ercan Olcay; Vakur Olgaç
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-08-15       Impact factor: 4.342

2.  Association of Statin Use with Increased Risk of Musculoskeletal Conditions: A Retrospective Cohort Study.

Authors:  Una E Makris; Carlos A Alvarez; Eric M Mortensen; Ishak A Mansi
Journal:  Drug Saf       Date:  2018-10       Impact factor: 5.606

3.  Tendon, tendon healing, hyperlipidemia and statins.

Authors:  Irfan Esenkaya; Koray Unay
Journal:  Muscles Ligaments Tendons J       Date:  2012-04-01

4.  Simvastatin and atorvastatin reduce the mechanical properties of tendon constructs in vitro and introduce catabolic changes in the gene expression pattern.

Authors:  Pernilla Eliasson; Rene B Svensson; Antonis Giannopoulos; Christian Eismark; Michael Kjær; Peter Schjerling; Katja M Heinemeier
Journal:  PLoS One       Date:  2017-03-06       Impact factor: 3.240

5.  Lipids, adiposity and tendinopathy: is there a mechanistic link? Critical review.

Authors:  Alex Scott; Johannes Zwerver; Navi Grewal; Agnetha de Sa; Thuraya Alktebi; David J Granville; David A Hart
Journal:  Br J Sports Med       Date:  2014-12-08       Impact factor: 13.800

  5 in total

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