Literature DB >> 23738266

Tendon, tendon healing, hyperlipidemia and statins.

Irfan Esenkaya1, Koray Unay.   

Abstract

Both hyperlipidemia and metabolic syndrome have adverse effect on tendon structure. Atorvastatin is most widely used antihyperlipidemic drug. Statins have adverse effects on the tendon. Many studies have analyzed the relationship between atorvastatin and skeletal muscles. Atorvastatin administered after the surgical repair of a ruptured tendon appears to affect revascularization, collagenization, inflammatory cell infiltration, and collagen construction. Therefore, further investigations on the effects of atorvastatin on tendon healing are needed.

Entities:  

Keywords:  hyperlipidemia; statins; tendon; tendon healing

Year:  2012        PMID： 23738266      PMCID： PMC3666488     

Source DB:  PubMed          Journal:  Muscles Ligaments Tendons J        ISSN： 2240-4554


  29 in total

Review 1.  Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a meta-analysis of 21 cohort studies including more than 300 000 persons.

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Journal:  Arch Intern Med       Date:  2007-09-10

2.  Regression of tendon xanthomas in patients with familial hypercholesterolemia treated with lovastatin.

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Journal:  South Med J       Date:  1990-09       Impact factor: 0.954

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Journal:  Arch Orthop Trauma Surg       Date:  1999       Impact factor: 3.067

Review 4.  Tendon injury and tendinopathy: healing and repair.

Authors:  Pankaj Sharma; Nicola Maffulli
Journal:  J Bone Joint Surg Am       Date:  2005-01       Impact factor: 5.284

5.  Cumulative effects of hypercholesterolemia on tendon biomechanics in a mouse model.

Authors:  David P Beason; Joseph A Abboud; Andrew F Kuntz; Rocco Bassora; Louis J Soslowsky
Journal:  J Orthop Res       Date:  2010-10-11       Impact factor: 3.494

6.  Tyrosine phosphorylation of the catalytic subunit p110 of phosphatidylinositol-3 kinase induced by HMG-CoA reductase inhibitor inhibits its kinase activity in L6 myoblasts.

Authors:  H Nakagawa; T Mutoh; T Kumano; M Kuriyama
Journal:  FEBS Lett       Date:  2001-11-09       Impact factor: 4.124

7.  The risk of tendon xanthomas in familial hypercholesterolaemia is influenced by variation in genes of the reverse cholesterol transport pathway and the low-density lipoprotein oxidation pathway.

Authors:  Daniëlla M Oosterveer; Jorie Versmissen; Mojgan Yazdanpanah; Joep C Defesche; John J P Kastelein; Eric J G Sijbrands
Journal:  Eur Heart J       Date:  2009-12-16       Impact factor: 29.983

Review 8.  Differences in characteristics and risk of cardiovascular disease in familial hypercholesterolemia patients with and without tendon xanthomas: a systematic review and meta-analysis.

Authors:  Daniëlla M Oosterveer; Jorie Versmissen; Mojgan Yazdanpanah; Taye H Hamza; Eric J G Sijbrands
Journal:  Atherosclerosis       Date:  2009-04-17       Impact factor: 5.162

9.  Dyslipidemia in Achilles tendinopathy is characteristic of insulin resistance.

Authors:  James Edmund Gaida; Lotta Alfredson; Zoltan Steven Kiss; Andrew Michael Wilson; Håkan Alfredson; Jill Leigh Cook
Journal:  Med Sci Sports Exerc       Date:  2009-06       Impact factor: 5.411

Review 10.  The vasculature and its role in the damaged and healing tendon.

Authors:  Steven A Fenwick; Brian L Hazleman; Graham P Riley
Journal:  Arthritis Res       Date:  2002-02-13
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  4 in total

1.  The effects of hyperlipidemia on rotator cuff diseases: a systematic review.

Authors:  Yang Yang; Jin Qu
Journal:  J Orthop Surg Res       Date:  2018-08-17       Impact factor: 2.359

2.  The impact of cholesterol deposits on the fibrillar architecture of the Achilles tendon in a rabbit model of hypercholesterolemia.

Authors:  Andrzej Steplewski; Jolanta Fertala; Ryan Tomlinson; Kevth'er Hoxha; Lin Han; Ocean Thakar; Jason Klein; Joseph Abboud; Andrzej Fertala
Journal:  J Orthop Surg Res       Date:  2019-06-10       Impact factor: 2.359

3.  Arthroscopic rotator cuff repair in patients over 70 years of age: a systematic review.

Authors:  Chiara Fossati; Carlo Stoppani; Alessandra Menon; Luca Pierannunzii; Riccardo Compagnoni; Pietro S Randelli
Journal:  J Orthop Traumatol       Date:  2021-02-18

4.  Lipids, adiposity and tendinopathy: is there a mechanistic link? Critical review.

Authors:  Alex Scott; Johannes Zwerver; Navi Grewal; Agnetha de Sa; Thuraya Alktebi; David J Granville; David A Hart
Journal:  Br J Sports Med       Date:  2014-12-08       Impact factor: 13.800
  4 in total

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