Literature DB >> 1989662

Flavone acetic acid--an interesting novel therapeutic agent or just another disappointment?

M C Bibby.   

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Year:  1991        PMID: 1989662      PMCID: PMC1971639          DOI: 10.1038/bjc.1991.2

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


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  30 in total

1.  Natural products as antitumor agents: direct versus indirect mechanisms of activity of flavonoids.

Authors:  R H Wiltrout; R L Hornung
Journal:  J Natl Cancer Inst       Date:  1988-04-20       Impact factor: 13.506

2.  Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy.

Authors:  M C Bibby; J A Double; P M Loadman; C V Duke
Journal:  J Natl Cancer Inst       Date:  1989-02-01       Impact factor: 13.506

3.  Characterization of the major metabolites of flavone acetic acid and comparison of their disposition in humans and mice.

Authors:  J Cummings; J A Double; M C Bibby; P Farmer; S Evans; D J Kerr; S B Kaye; J F Smyth
Journal:  Cancer Res       Date:  1989-07-01       Impact factor: 12.701

4.  Influence of site on the chemosensitivity of transplantable murine colon tumours to flavone acetic acid (LM975, NSC 347512).

Authors:  M C Bibby; R M Phillips; J A Double
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

5.  Effect of flavone acetic acid on Lewis lung carcinoma: evidence for an indirect effect.

Authors:  G J Finlay; G P Smith; L M Fray; B C Baguley
Journal:  J Natl Cancer Inst       Date:  1988-04-20       Impact factor: 13.506

6.  Antiproliferative properties of flavone acetic acid (NSC 347512) (LM 975), a new anticancer agent.

Authors:  L S Capolongo; G Balconi; P Ubezio; R Giavazzi; G Taraboletti; A Regonesi; O C Yoder; M D'Incalci
Journal:  Eur J Cancer Clin Oncol       Date:  1987-10

7.  Immunomodulation of natural killer cell activity by flavone acetic acid: occurrence via induction of interferon alpha/beta.

Authors:  R L Hornung; H A Young; W J Urba; R H Wiltrout
Journal:  J Natl Cancer Inst       Date:  1988-10-05       Impact factor: 13.506

8.  Enhancement of natural killer activity in human peripheral blood by flavone acetic acid.

Authors:  W J Urba; D L Longo; F A Lombardo; R B Weiss
Journal:  J Natl Cancer Inst       Date:  1988-06-01       Impact factor: 13.506

9.  Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer.

Authors:  R H Wiltrout; M R Boyd; T C Back; R R Salup; J A Arthur; R L Hornung
Journal:  J Immunol       Date:  1988-05-01       Impact factor: 5.422

10.  Response to flavone acetic acid (NSC 347512) of primary and metastatic human colorectal carcinoma xenografts.

Authors:  R Giavazzi; A Garofalo; G Damia; S Garattini; M D'Incalci
Journal:  Br J Cancer       Date:  1988-03       Impact factor: 7.640

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  7 in total

Review 1.  Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.

Authors:  Zhiyan Xiao; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal:  Med Res Rev       Date:  2015-09-11       Impact factor: 12.944

2.  Selectivity and potency; are we doing the right things to find anti-cancer agents with these properties?

Authors:  J A Double
Journal:  Br J Cancer       Date:  1992-02       Impact factor: 7.640

Review 3.  Making the most of rodent tumour systems in cancer drug discovery.

Authors:  M C Bibby
Journal:  Br J Cancer       Date:  1999-04       Impact factor: 7.640

4.  Clinical aspects of a phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent.

Authors:  M B Jameson; P I Thompson; B C Baguley; B D Evans; V J Harvey; D J Porter; M R McCrystal; M Small; K Bellenger; L Gumbrell; G W Halbert; P Kestell
Journal:  Br J Cancer       Date:  2003-06-16       Impact factor: 7.640

5.  Flavone acetic acid (FAA) with recombinant interleukin-2 (rIL-2) in advanced malignant melanoma. III: Cytokine studies.

Authors:  C Haworth; S M O'Reilly; E Chu; G J Rustin; M Feldmann
Journal:  Br J Cancer       Date:  1993-06       Impact factor: 7.640

6.  Tumour concentrations of flavone acetic acid (FAA) in human melanoma: comparison with mouse data.

Authors:  T S Maughan; R Ward; I Dennis; D J Honess; P Workman; N M Bleehen
Journal:  Br J Cancer       Date:  1992-09       Impact factor: 7.640

7.  Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK.

Authors:  D R Newell; K M Searle; N B Westwood; S S Burtles
Journal:  Br J Cancer       Date:  2003-08-04       Impact factor: 7.640

  7 in total

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