Literature DB >> 19884378

BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa.

Laurent Poirel1, Jean-Denis Docquier, Filomena De Luca, Annemie Verlinde, Louis Ide, Gian Maria Rossolini, Patrice Nordmann.   

Abstract

A Pseudomonas aeruginosa isolate recovered in Belgium produced a novel extended-spectrum ss-lactamase, BEL-2, differing from BEL-1 by a single Leu162Phe substitution. That modification significantly altered the kinetic properties of the enzyme, increasing its affinity for expanded-spectrum cephalosporins. The bla(BEL-2) gene was identified from a P. aeruginosa isolate clonally related to another bla(BEL-1)-positive isolate.

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Year:  2009        PMID: 19884378      PMCID: PMC2798549          DOI: 10.1128/AAC.00859-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  29 in total

1.  An SHV-derived extended-spectrum beta-lactamase in Pseudomonas aeruginosa.

Authors:  T Naas; L Philippon; L Poirel; E Ronco; P Nordmann
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

2.  Integron- and carbenicillinase-mediated reduced susceptibility to amoxicillin-clavulanic acid in isolates of multidrug-resistant Salmonella enterica serotype typhimurium DT104 from French patients.

Authors:  L Poirel; M Guibert; S Bellais; T Naas; P Nordmann
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

3.  Emergence of the extended-spectrum beta-lactamase GES-1 in a Pseudomonas aeruginosa strain from Brazil: report from the SENTRY antimicrobial surveillance program.

Authors:  Mariana Castanheira; Rodrigo E Mendes; Timothy R Walsh; Ana C Gales; Ronald N Jones
Journal:  Antimicrob Agents Chemother       Date:  2004-06       Impact factor: 5.191

4.  Rapid detection and sequence-specific differentiation of extended-spectrum beta-lactamase GES-2 from Pseudomonas aeruginosa by use of a real-time PCR assay.

Authors:  Gerhard F Weldhagen
Journal:  Antimicrob Agents Chemother       Date:  2004-10       Impact factor: 5.191

5.  A standard numbering scheme for the class A beta-lactamases.

Authors:  R P Ambler; A F Coulson; J M Frère; J M Ghuysen; B Joris; M Forsman; R C Levesque; G Tiraby; S G Waley
Journal:  Biochem J       Date:  1991-05-15       Impact factor: 3.857

6.  PER-1- and OXA-10-like beta-lactamases in ceftazidime-resistant Pseudomonas aeruginosa isolates from intensive care unit patients in Istanbul, Turkey.

Authors:  Z Aktaş; L Poirel; M Salcioğlu; P E Ozcan; K Midilli; C Bal; O Anğ; P Nordmann
Journal:  Clin Microbiol Infect       Date:  2005-03       Impact factor: 8.067

7.  PER-1 is still widespread in Turkish hospitals among Pseudomonas aeruginosa and Acinetobacter spp.

Authors:  Fetiye Kolayli; Gulcin Gacar; Aynur Karadenizli; Ahmet Sanic; Haluk Vahaboglu
Journal:  FEMS Microbiol Lett       Date:  2005-08-15       Impact factor: 2.742

8.  Factors affecting the isolation of CCC DNA from Streptomyces lividans and Escherichia coli.

Authors:  T Kieser
Journal:  Plasmid       Date:  1984-07       Impact factor: 3.466

9.  In vivo selection of a chromosomally encoded beta-lactamase variant conferring ceftazidime resistance in Klebsiella oxytoca.

Authors:  Hedi Mammeri; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2003-12       Impact factor: 5.191

10.  Multifocal detection of multidrug-resistant Pseudomonas aeruginosa producing the PER-1 extended-spectrum beta-lactamase in Northern Italy.

Authors:  Laura Pagani; Elisabetta Mantengoli; Roberta Migliavacca; Elisabetta Nucleo; Simona Pollini; Melissa Spalla; Rossana Daturi; Egidio Romero; Gian Maria Rossolini
Journal:  J Clin Microbiol       Date:  2004-06       Impact factor: 5.948

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  9 in total

1.  Detection of β-lactamase encoding genes in feces, soil and water from a Brazilian pig farm.

Authors:  João Pedro Rueda Furlan; Eliana Guedes Stehling
Journal:  Environ Monit Assess       Date:  2018-01-10       Impact factor: 2.513

2.  The class A β-lactamase FTU-1 is native to Francisella tularensis.

Authors:  Nuno T Antunes; Hilary Frase; Marta Toth; Sergei B Vakulenko
Journal:  Antimicrob Agents Chemother       Date:  2011-11-14       Impact factor: 5.191

3.  A novel extended-spectrum β-lactamase, SGM-1, from an environmental isolate of Sphingobium sp.

Authors:  Toni L Lamoureaux; Viktoria Vakulenko; Marta Toth; Hilary Frase; Sergei B Vakulenko
Journal:  Antimicrob Agents Chemother       Date:  2013-05-28       Impact factor: 5.191

4.  Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum β-Lactamase and Its Complexes with Moxalactam and Imipenem.

Authors:  Cecilia Pozzi; Filomena De Luca; Manuela Benvenuti; Laurent Poirel; Patrice Nordmann; Gian Maria Rossolini; Stefano Mangani; Jean-Denis Docquier
Journal:  Antimicrob Agents Chemother       Date:  2016-11-21       Impact factor: 5.191

5.  Characterization of multidrug-resistant and virulent Klebsiella pneumoniae strains belonging to the high-risk clonal group 258 (CG258) isolated from inpatients in northeastern Brazil.

Authors:  Rafael Nakamura-Silva; Mariana Oliveira-Silva; João Pedro Rueda Furlan; Eliana Guedes Stehling; Carlos Eduardo Saraiva Miranda; André Pitondo-Silva
Journal:  Arch Microbiol       Date:  2021-06-10       Impact factor: 2.552

6.  Integrase-Mediated Recombination of the bel-1 Gene Cassette Encoding the Extended-Spectrum β-Lactamase BEL-1.

Authors:  Nacim Bouheraoua; Laurent Poirel; Baptiste Bourreau; Rémy Bonnin; Laurent Laroche; Thierry Naas; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2018-04-26       Impact factor: 5.191

7.  Pseudomonas aeruginosa: resistance to the max.

Authors:  Keith Poole
Journal:  Front Microbiol       Date:  2011-04-05       Impact factor: 5.640

8.  Colonization of long-term care facility residents in three Italian Provinces by multidrug-resistant bacteria.

Authors:  Elisabetta Nucleo; Mariasofia Caltagirone; Vittoria Mattioni Marchetti; Roberto D'Angelo; Elena Fogato; Massimo Confalonieri; Camilla Reboli; Albert March; Ferisa Sleghel; Gertrud Soelva; Elisabetta Pagani; Richard Aschbacher; Roberta Migliavacca; Laura Pagani
Journal:  Antimicrob Resist Infect Control       Date:  2018-03-06       Impact factor: 4.887

9.  Detection of P. aeruginosa harboring bla CTX-M-2, bla GES-1 and bla GES-5, bla IMP-1 and bla SPM-1 causing infections in Brazilian tertiary-care hospital.

Authors:  Milena Polotto; Tiago Casella; Maria Gabriela de Lucca Oliveira; Fernando G Rúbio; Mauricio L Nogueira; Margarete Tg de Almeida; Mara Cl Nogueira
Journal:  BMC Infect Dis       Date:  2012-08-03       Impact factor: 3.090

  9 in total

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