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Literature DB >> 19871597

CENTRIFUGATION STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : THE RELATIVE SIZES OF FREE AND COMBINED VIRUS.

Abstract

A technique has been devised for obtaining free or uncombined pneumonia virus of mice (PVM). Free PVM, liberated from infected mouse lungs by means of this technique, is infectious and causes hemagglutination directly. The results of quantitative studies carried out in the high speed angle centrifuge indicate that the free virus is relatively small, with dimensions of the order of 40 millimicrons. When it is in combination with lung tissue particles, PVM appears to be a relatively large virus with minimal dimensions of the order of 140 millimicrons. Non-infectious virus particles, released from combination with lung tissue particles by heating, are similar to the infectious free virus in size.

Entities: Disease Species

Keywords: PNEUMONIA/virus; VIRUSES

Mesh：

Year: 1947 PMID： 19871597 PMCID： PMC2135667 DOI： 10.1084/jem.85.1.23

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

6 in total

4. STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : III. HEMAGGLUTINATION BY THE VIRUS; THE OCCURRENCE OF COMBINATION BETWEEN THE VIRUS AND A TISSUE SUBSTANCE.

Authors: E C Curnen; F L Horsfall
Journal: J Exp Med Date: 1946-01-31 Impact factor: 14.307

5. A LATENT VIRUS IN NORMAL MICE CAPABLE OF PRODUCING PNEUMONIA IN ITS NATURAL HOST.

Authors: F L Horsfall; R G Hahn
Journal: J Exp Med Date: 1940-02-29 Impact factor: 14.307

6. STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : II. IMMUNOLOGICAL EVIDENCE OF LATENT INFECTION WITH THE VIRUS IN NUMEROUS MAMMALIAN SPECIES.

Authors: F L Horsfall; E C Curnen
Journal: J Exp Med Date: 1946-01-01 Impact factor: 14.307

6 in total

8 in total

1. Hemagglutination by measles virus. I. The production of hemagglutinin in tissue culture and the influence of different conditions on the hemagglutinating system.

Authors: E NORRBY
Journal: Arch Gesamte Virusforsch Date: 1962

2. Characteristics of the multiplication cycle of pneumonia virus of mice (PVM).

Authors: H S GINSBERG; F L HORSFALL
Journal: J Exp Med Date: 1951-02 Impact factor: 14.307

3. Studies on pneumonia virus of mice (PVM) in cell culture. I. Replication in baby hamster kidney cells and properties of the virus.

Authors: D H Harter; P W Choppin
Journal: J Exp Med Date: 1967-08-01 Impact factor: 14.307

4. The dependence of the pathological lesion upon the multiplication of pneumonia virus of mice (PVM); kinetic relation between the degree of viral multiplication and the extent of pneumonia.

Authors: F L HORSFALL; H S GINSBERG
Journal: J Exp Med Date: 1951-02 Impact factor: 14.307

5. THE MODIFYING EFFECTS OF CERTAIN SUBSTANCES OF BACTERIAL ORIGIN ON THE COURSE OF INFECTION WITH PNEUMONIA VIRUS OF MICE (PVM).

Authors: F L Horsfall; M McCarty
Journal: J Exp Med Date: 1947-05-31 Impact factor: 14.307

6. Further studies on the associative reactions of pneumonia virus of mice and influenza viruses; combination with various animal tissues and adsorbents.

Authors: F M DAVENPORT; F L HORSFALL
Journal: J Exp Med Date: 1950-01-01 Impact factor: 14.307

7. STUDIES ON A LUNG TISSUE COMPONENT WHICH COMBINES WITH PNEUMONIA VIRUS OF MICE (PVM).

Authors: M Volkert; F L Horsfall
Journal: J Exp Med Date: 1947-10-31 Impact factor: 14.307

8. Studies on pneumonia virus of mice (PVM) in cell culture. II. Structure and morphogenesis of the virus particle.

Authors: R W Compans; D H Harter; P W Choppin
Journal: J Exp Med Date: 1967-08-01 Impact factor: 14.307