Literature DB >> 19871520

STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : II. EFFECT OF DESOXYRIBONUCLEASE ON THE BIOLOGICAL ACTIVITY OF THE TRANSFORMING SUBSTANCE.

M McCarty1, O T Avery.   

Abstract

It has been shown that extremely minute amounts of purified preparations of desoxyribonuclease are capable of bringing about the complete and irreversible inactivation of the transforming substance of Pneumococcus Type III. The significance of the effect of the enzyme, and its bearing on the chemical nature of the transforming substance, together with certain considerations concerning the biological specificity of desoxyribonucleic acids in general, are discussed.

Year:  1946        PMID: 19871520      PMCID: PMC2135575     

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  2 in total

1.  STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III.

Authors:  O T Avery; C M Macleod; M McCarty
Journal:  J Exp Med       Date:  1944-02-01       Impact factor: 14.307

2.  REVERSIBLE INACTIVATION OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES.

Authors:  M McCarty
Journal:  J Exp Med       Date:  1945-05-01       Impact factor: 14.307

  2 in total
  22 in total

1.  Contribution on the biochemical investigation of external factors required for type transformation in the pneumococcus.

Authors:  M KOHOUTOVA
Journal:  Folia Microbiol (Praha)       Date:  1962-01       Impact factor: 2.099

2.  [Induced mutations in Leptospira].

Authors:  H SCHLOSSBERGER
Journal:  Z Hyg Infektionskr       Date:  1950

3.  PURIFICATION AND PROPERTIES OF DESOXYRIBONUCLEASE ISOLATED FROM BEEF PANCREAS.

Authors:  M McCarty
Journal:  J Gen Physiol       Date:  1946-01-20       Impact factor: 4.086

4.  [On the transformation of nodular bacteria].

Authors:  D Wagenbreth
Journal:  Arch Mikrobiol       Date:  1965-10-14

Review 5.  DNA methylation and its basic function.

Authors:  Lisa D Moore; Thuc Le; Guoping Fan
Journal:  Neuropsychopharmacology       Date:  2012-07-11       Impact factor: 7.853

6.  Histone Acid Extraction and High Throughput Mass Spectrometry to Profile Histone Modifications in Arabidopsis thaliana.

Authors:  Ray Scheid; James A Dowell; Dean Sanders; Jianjun Jiang; John M Denu; Xuehua Zhong
Journal:  Curr Protoc       Date:  2022-08

Review 7.  Multiple forms of deoxyribonuclease I.

Authors:  T H Liao
Journal:  Mol Cell Biochem       Date:  1981-01-20       Impact factor: 3.396

8.  17β-Estradiol Increases Non-CpG Methylation in Exon 1 of the Rainbow Trout (Oncorhynchus mykiss) MyoD Gene.

Authors:  Prasanthi P Koganti; Jian Wang; Beth Cleveland; Jianbo Yao
Journal:  Mar Biotechnol (NY)       Date:  2017-06-03       Impact factor: 3.619

Review 9.  DNA methyltransferases in hematological malignancies.

Authors:  Nguyet-Minh Hoang; Lixin Rui
Journal:  J Genet Genomics       Date:  2020-07-24       Impact factor: 4.275

10.  A path to discovery: the career of Maclyn McCarty.

Authors:  Joshua Lederberg; Emil C Gotschlich
Journal:  PLoS Biol       Date:  2005-10-11       Impact factor: 8.029

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