Literature DB >> 19869085

THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : THIRD PAPER.

M Heidelberger1, W F Goebel, O T Avery.   

Abstract

1. Refinements in the methods for the isolation of the soluble specific substances of Types II and III pneumococcus are described. These improvements have resulted in the isolation of the end-products in a form free from nitrogen and of enhanced activity with immune serum. 2. The soluble specific substance of Type I pneumococcus is described and shown to differ sharply from the corresponding substances of the other two types, each of which, in turn, differs from the other. 3. Progress is reported on the identification of the sugar units from which the polysaccharides are built up. 4. The evidence so far accumulated is believed to favor strongly the view that the polysaccharides isolated are the actual specific substances of Pneumococcus.

Entities:  

Year:  1925        PMID: 19869085      PMCID: PMC2131056          DOI: 10.1084/jem.42.5.727

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  3 in total

1.  THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : SECOND PAPER.

Authors:  M Heidelberger; O T Avery
Journal:  J Exp Med       Date:  1924-08-31       Impact factor: 14.307

2.  IMMUNOLOGICAL RELATIONSHIPS OF CELL CONSTITUENTS OF PNEUMOCOCCUS : SECOND PAPER.

Authors:  O T Avery; M Heidelberger
Journal:  J Exp Med       Date:  1925-08-31       Impact factor: 14.307

3.  THE ELABORATION OF SPECIFIC SOLUBLE SUBSTANCE BY PNEUMOCOCCUS DURING GROWTH.

Authors:  A R Dochez; O T Avery
Journal:  J Exp Med       Date:  1917-10-01       Impact factor: 14.307

  3 in total
  42 in total

1.  Sortase-conjugation generates a capsule vaccine that protects guinea pigs against Bacillus anthracis.

Authors:  Gabriella Garufi; Ya-Ting Wang; So-Young Oh; Hannah Maier; Dominique M Missiakas; Olaf Schneewind
Journal:  Vaccine       Date:  2012-03-23       Impact factor: 3.641

2.  CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : I. THE SYNTHESIS OFp-AMINOPHENOL beta-GLUCOSIDE, p-AMINOPHENOL beta-GALACTOSIDE, AND THEIR COUPLING WITH SERUM GLOBULIN.

Authors:  W F Goebel; O T Avery
Journal:  J Exp Med       Date:  1929-09-30       Impact factor: 14.307

3.  Colicine K. I. The production of colicine K in media maintained at constant pH.

Authors:  W F GOEBEL; G T BARRY; T SHEDLOVSKY
Journal:  J Exp Med       Date:  1956-05-01       Impact factor: 14.307

4.  THE ISOLATION OF THE BLOOD GROUP A SPECIFIC SUBSTANCE FROM COMMERCIAL PEPTONE.

Authors:  W F Goebel
Journal:  J Exp Med       Date:  1938-07-31       Impact factor: 14.307

5.  ON THE PRESENCE IN ANTIPNEUMOCOCCUS SERUM OF TYPE-SPECIFIC PROTECTIVE ANTIBODY NOT NEUTRALIZED BY HOMOLOGOUS SPECIFIC SOLUBLE SUBSTANCE.

Authors:  A B Sabin
Journal:  J Exp Med       Date:  1931-01-01       Impact factor: 14.307

6.  The immunological specificity of type II Pneumococcus and its separation into partial specificities. II.

Authors:  M HEIDELBERGER
Journal:  J Exp Med       Date:  1960-01-01       Impact factor: 14.307

7.  SPECIFIC ANTIBODY RESPONSE OF HUMAN SUBJECTS TO INTRACUTANEOUS INJECTION OF PNEUMOCOCCUS PRODUCTS.

Authors:  M Finland; W D Sutliff
Journal:  J Exp Med       Date:  1932-05-31       Impact factor: 14.307

8.  CUTANEOUS REACTIONS IN PNEUMONIA. THE DEVELOPMENT OF ANTIBODIES FOLLOWING THE INTRADERMAL INJECTION OF TYPE-SPECIFIC POLYSACCHARIDE.

Authors:  T Francis; W S Tillett
Journal:  J Exp Med       Date:  1930-09-30       Impact factor: 14.307

9.  CARBOHYDRATES ADSORBED ON COLLOIDS AS ANTIGENS.

Authors:  J Zozaya
Journal:  J Exp Med       Date:  1932-02-29       Impact factor: 14.307

10.  A "SOLUBLE SPECIFIC SUBSTANCE" DERIVED FROM GUM ARABIC.

Authors:  M Heidelberger; O T Avery; W F Goebel
Journal:  J Exp Med       Date:  1929-04-30       Impact factor: 14.307

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