Literature DB >> 19865047

The influence of age, bone quality and body mass index on periprosthetic femoral fractures: a biomechanical laboratory study.

Eike Jakubowitz1, Jörn Bengt Seeger, Jan Philippe Kretzer, Christian Heisel, Jennifer Aileen Kleinhans, Marc Thomsen.   

Abstract

BACKGROUND: A periprosthetic femoral fracture after total hip arthroplasty is a serious but uncommon complication, and therefore difficult to analyze clinically in scientifically and statistically valid study samples. With the aim of preventing these fractures the purpose of this study was to investigate potential risk factors associated with cementless hip arthroplasty in a standardized laboratory setup. Additionally, we aimed to clarify if the treatment with a cementless hip stem is fraught with higher risk of periprosthetic fracture for older patients compared to younger patients. MATERIAL/
METHODS: A biomechanical setup was developed to provide analysis on sixteen femoral specimens of different age. A cementless hip stem was implanted into the specimens and loads - representing hip contact forces - were applied under standardized conditions until fracture occurred. The femurs were divided into two age groups (<70 and >or=77 years of age).
RESULTS: The elderly specimens fractured at significantly lower maximum forces (<70: Fmax=5,308N; >or=77: Fmax=2,519N; p<0.01). Maximum fracture loads were found to correlate strongly with age (p=0.01), BMD (e.g. for the Ward's triangle: p<0.01) and BMI (p=0.04).
CONCLUSIONS: In patients with advanced age treated with cementless hip stems the risk of suffering a periprosthetic fracture is significantly higher. It increases in patients with an age of 80 years or older, a Ward's triangle BMD below 0.500 g/cm2 and a BMI >33 kg/m2. Whereas one single factor must not be viewed as an exclusion criterion for a cementless hip stem treatment, cumulation of these factors should alert the orthopaedic surgeon.

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Mesh:

Year:  2009        PMID: 19865047

Source DB:  PubMed          Journal:  Med Sci Monit        ISSN: 1234-1010


  10 in total

Review 1.  Surgical treatment options in patients with impaired bone quality.

Authors:  Norman A Johanson; Jody Litrenta; Jay M Zampini; Frederic Kleinbart; Haviva M Goldman
Journal:  Clin Orthop Relat Res       Date:  2011-08       Impact factor: 4.176

Review 2.  Incidence and predisposing factors of periprosthetic proximal femoral fractures: a literature review.

Authors:  Claudia C Sidler-Maier; James P Waddell
Journal:  Int Orthop       Date:  2015-03-27       Impact factor: 3.075

3.  Strontium fructose 1,6-diphosphate prevents bone loss in a rat model of postmenopausal osteoporosis via the OPG/RANKL/RANK pathway.

Authors:  Bo Ma; Qi Zhang; Di Wu; Yong-lu Wang; Ying-ying Hu; Yan-ping Cheng; Zhen-dong Yang; Ya-ya Zheng; Han-Jie Ying
Journal:  Acta Pharmacol Sin       Date:  2012-03-19       Impact factor: 6.150

Review 4.  Periprosthetic fractures: concepts of biomechanical in vitro investigations.

Authors:  Eike Jakubowitz; Jörn Bengt Seeger
Journal:  Int Orthop       Date:  2015-08-21       Impact factor: 3.075

5.  32k Da protein improve ovariectomy-induced bone loss in rats.

Authors:  Yingtang Zhou; Shenhua Jiang; Jing Chen; Tao Wang; DengZhao Jiang; Hui Chen; Huan Yu
Journal:  Prion       Date:  2013-08-07       Impact factor: 3.931

Review 6.  Salvage of a femoral nonunion after primary non-Hodgkin's lymphoma of bone: a case report and literature review.

Authors:  Xue Tao Xie; You Shui Gao; Chang Qing Zhang
Journal:  Med Sci Monit       Date:  2011-11

7.  Overstretching Expectations May Endanger the Success of the "Millennium Surgery".

Authors:  Alwina Bender; Philipp Damm; Hagen Hommel; Georg N Duda
Journal:  Front Bioeng Biotechnol       Date:  2022-02-14

8.  Bone Loss Following Cementless Hemiarthroplasty for the Treatment of Femoral Neck Fracture.

Authors:  Mert Murat; Cenk Ermutlu; Ethem Ayhan Unkar; Sertaç Topalhafızoglu; Ahmet Şenel; Yusuf Öztürkmen
Journal:  Indian J Orthop       Date:  2020-01-31       Impact factor: 1.251

9.  Is Obesity Associated with Higher Complication Rates in Total Hip Arthroplasty for High-Riding Dysplastic Hips?

Authors:  Necdet Saglam; Deniz Gulabi; Anil Agar; Ahmet Can Erdem; Levent Bayam; Mehmet Erdem
Journal:  Indian J Orthop       Date:  2021-01-13       Impact factor: 1.251

10.  Effects of remifemin treatment on bone integrity and remodeling in rats with ovariectomy-induced osteoporosis.

Authors:  Guangxia Cui; Huijie Leng; Ke Wang; Jianwei Wang; Sainan Zhu; Jing Jia; Xing Chen; Weiguang Zhang; Lihua Qin; Wenpei Bai
Journal:  PLoS One       Date:  2013-12-09       Impact factor: 3.240

  10 in total

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