Literature DB >> 19859929

Specificity and mechanism of Acinetobacter baumanii nicotinamidase: implications for activation of the front-line tuberculosis drug pyrazinamide.

Paul K Fyfe1, Vincenzo A Rao, Aleksandra Zemla, Scott Cameron, William N Hunter.   

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Year:  2009        PMID: 19859929      PMCID: PMC3465764          DOI: 10.1002/anie.200903407

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  13 in total

1.  Characterization of new mutations in pyrazinamide-resistant strains of Mycobacterium tuberculosis and identification of conserved regions important for the catalytic activity of the pyrazinamidase PncA.

Authors:  N Lemaitre; W Sougakoff; C Truffot-Pernot; V Jarlier
Journal:  Antimicrob Agents Chemother       Date:  1999-07       Impact factor: 5.191

Review 2.  Enzymology of NAD+ synthesis.

Authors:  G Magni; A Amici; M Emanuelli; N Raffaelli; S Ruggieri
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1999

Review 3.  The paradox of pyrazinamide: an update on the molecular mechanisms of pyrazinamide resistance in Mycobacteria.

Authors:  Pushpendra Singh; A K Mishra; S K Malonia; D S Chauhan; V D Sharma; K Venkatesan; V M Katoch
Journal:  J Commun Dis       Date:  2006-03

4.  Catalytic mechanism in papain family of cysteine peptidases.

Authors:  A C Storer; R Ménard
Journal:  Methods Enzymol       Date:  1994       Impact factor: 1.600

5.  Geometry of metal-ligand interactions in proteins.

Authors:  M M Harding
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2001-03

Review 6.  The curious characteristics of pyrazinamide: a review.

Authors:  Y Zhang; D Mitchison
Journal:  Int J Tuberc Lung Dis       Date:  2003-01       Impact factor: 2.373

7.  Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis.

Authors:  O Zimhony; J S Cox; J T Welch; C Vilchèze; W R Jacobs
Journal:  Nat Med       Date:  2000-09       Impact factor: 53.440

8.  Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase.

Authors:  Hua Zhang; Jiao-Yu Deng; Li-Jun Bi; Ya-Feng Zhou; Zhi-Ping Zhang; Cheng-Gang Zhang; Ying Zhang; Xian-En Zhang
Journal:  FEBS J       Date:  2008-01-14       Impact factor: 5.542

Review 9.  Overview of anti-tuberculosis (TB) drugs and their resistance mechanisms.

Authors:  Ruiru Shi; Nobunori Itagaki; Isamu Sugawara
Journal:  Mini Rev Med Chem       Date:  2007-11       Impact factor: 3.862

Review 10.  The nitrilase superfamily: classification, structure and function.

Authors:  H C Pace; C Brenner
Journal:  Genome Biol       Date:  2001-01-15       Impact factor: 13.583

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  29 in total

1.  Genomics-driven reconstruction of acinetobacter NAD metabolism: insights for antibacterial target selection.

Authors:  Leonardo Sorci; Ian Blaby; Jessica De Ingeniis; Svetlana Gerdes; Nadia Raffaelli; Valérie de Crécy Lagard; Andrei Osterman
Journal:  J Biol Chem       Date:  2010-10-06       Impact factor: 5.157

2.  Kinetics and inhibition of nicotinamidase from Mycobacterium tuberculosis.

Authors:  Derrick R Seiner; Subray S Hegde; John S Blanchard
Journal:  Biochemistry       Date:  2010-11-09       Impact factor: 3.162

3.  Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism.

Authors:  Jarrod B French; Yana Cen; Tracy L Vrablik; Ping Xu; Eleanor Allen; Wendy Hanna-Rose; Anthony A Sauve
Journal:  Biochemistry       Date:  2010-11-15       Impact factor: 3.162

4.  Withdrawn

Authors: 
Journal:  Infect Disord Drug Targets       Date:  2012-11-16

5.  Mechanisms of Pyrazinamide Action and Resistance.

Authors:  Ying Zhang; Wanliang Shi; Wenhong Zhang; Denis Mitchison
Journal:  Microbiol Spectr       Date:  2013

6.  High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes .

Authors:  Jarrod B French; Yana Cen; Anthony A Sauve; Steven E Ealick
Journal:  Biochemistry       Date:  2010-09-20       Impact factor: 3.162

7.  Role of metal ions on the activity of Mycobacterium tuberculosis pyrazinamidase.

Authors:  Patricia Sheen; Patricia Ferrer; Robert H Gilman; Gina Christiansen; Paola Moreno-Román; Andrés H Gutiérrez; Jun Sotelo; Wilfredo Evangelista; Patricia Fuentes; Daniel Rueda; Myra Flores; Paula Olivera; José Solis; Alessandro Pesaresi; Doriano Lamba; Mirko Zimic
Journal:  Am J Trop Med Hyg       Date:  2012-07       Impact factor: 2.345

8.  Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae.

Authors:  Brian C Smith; Mark A Anderson; Kelly A Hoadley; James L Keck; W Wallace Cleland; John M Denu
Journal:  Biochemistry       Date:  2011-12-29       Impact factor: 3.162

9.  Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates from Korea and analysis of the correlation between the mutations and pyrazinamidase activity.

Authors:  Jee-Hyun Yoon; Ji-Sun Nam; Kyung-Jin Kim; Young-Tae Ro
Journal:  World J Microbiol Biotechnol       Date:  2014-07-18       Impact factor: 3.312

10.  Nicotinamidase/pyrazinamidase of Mycobacterium tuberculosis forms homo-dimers stabilized by disulfide bonds.

Authors:  Daniel Rueda; Patricia Sheen; Robert H Gilman; Carlos Bueno; Marco Santos; Victoria Pando-Robles; Cesar V Batista; Mirko Zimic
Journal:  Tuberculosis (Edinb)       Date:  2014-08-24       Impact factor: 3.131

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