PURPOSE: To determine whether regional changes in lung ventilation in a group of pediatric cystic fibrosis (CF) patients following a course of chest physiotherapy could be detected with (3)He MRI. MATERIALS AND METHODS: The reproducibility of lung ventilation volume measurements obtained with (3)He lung magnetic resonance imaging (MRI) was established in a group of five children with CF age 6-15 years. The same methodology was then used to evaluate whether standard chest physiotherapy (percussion and drainage) had any immediate effect on regional ventilated lung volumes in a further group of nine age-matched CF children (5-15 years). RESULTS: Global lung ventilation volumes remained the same within the limits of sensitivity derived from the reproducibility study; however, regional lung ventilation was observed to change in most patients after therapy. CONCLUSION: (3)He MRI can be successfully used in children with CF, and has the sensitivity to detect regional quantitative changes in lung ventilation following chest physiotherapy.
PURPOSE: To determine whether regional changes in lung ventilation in a group of pediatric cystic fibrosis (CF) patients following a course of chest physiotherapy could be detected with (3)He MRI. MATERIALS AND METHODS: The reproducibility of lung ventilation volume measurements obtained with (3)He lung magnetic resonance imaging (MRI) was established in a group of five children with CF age 6-15 years. The same methodology was then used to evaluate whether standard chest physiotherapy (percussion and drainage) had any immediate effect on regional ventilated lung volumes in a further group of nine age-matched CFchildren (5-15 years). RESULTS: Global lung ventilation volumes remained the same within the limits of sensitivity derived from the reproducibility study; however, regional lung ventilation was observed to change in most patients after therapy. CONCLUSION: (3)He MRI can be successfully used in children with CF, and has the sensitivity to detect regional quantitative changes in lung ventilation following chest physiotherapy.
Authors: Mu He; Scott H Robertson; S Sivaram Kaushik; Matthew S Freeman; Rohan S Virgincar; John Davies; Jane Stiles; William M Foster; H Page McAdams; Bastiaan Driehuys Journal: Magn Reson Imaging Date: 2015-04-30 Impact factor: 2.546
Authors: Nanae Tsuchiya; Mark L Schiebler; Michael D Evans; Robert V Cadman; Ronald L Sorkness; Robert F Lemanske; Daniel J Jackson; Nizar N Jarjour; Loren C Denlinger; Sean B Fain Journal: Pediatr Radiol Date: 2020-01-24
Authors: Laura L Walkup; Robert P Thomen; Teckla G Akinyi; Erin Watters; Kai Ruppert; John P Clancy; Jason C Woods; Zackary I Cleveland Journal: Pediatr Radiol Date: 2016-08-05
Authors: Robert P Thomen; Laura L Walkup; David J Roach; Zackary I Cleveland; John P Clancy; Jason C Woods Journal: J Cyst Fibros Date: 2016-07-29 Impact factor: 5.482
Authors: Tokihiro Yamamoto; Sven Kabus; Jens von Berg; Cristian Lorenz; Melody P Chung; Julian C Hong; Billy W Loo; Paul J Keall Journal: Acad Radiol Date: 2012-09-10 Impact factor: 3.173
Authors: Rohan S Virgincar; Zackary I Cleveland; S Sivaram Kaushik; Matthew S Freeman; John Nouls; Gary P Cofer; Santiago Martinez-Jimenez; Mu He; Monica Kraft; Jan Wolber; H Page McAdams; Bastiaan Driehuys Journal: NMR Biomed Date: 2012-10-13 Impact factor: 4.044
Authors: Lucia Flors; John P Mugler; Eduard E de Lange; Grady W Miller; Jaime F Mata; Nick Tustison; Iulian C Ruset; F William Hersman; Talissa A Altes Journal: J Thorac Imaging Date: 2016-09 Impact factor: 3.000