Literature DB >> 19853156

Cell-based therapy for ischemic heart disease: a clinical update.

Jeremy L Herrmann1, Aaron M Abarbanell, Brent R Weil, Yue Wang, Meijing Wang, Jiangning Tan, Daniel R Meldrum.   

Abstract

Progenitor cell therapy is a promising treatment for ischemic heart disease. Early clinical trials of autologous bone marrow-derived progenitor cell therapy for acute and chronic myocardial ischemia showed modest functional improvements after cell delivery; however, the duration of these benefits remains unclear. Ongoing investigations continue to enhance our understanding of the mechanisms by which progenitor and stem cells function and how their survival and cardioprotective abilities can be improved. This review discusses: (1) relevant progenitor and stem cells in myocardial regenerative therapy, (2) routes of cell delivery to ischemic myocardium, (3) clinical trials investigating bone marrow-derived progenitor cell therapy for myocardial ischemia, and (4) future directions of the field.

Entities:  

Mesh：

Year:  2009        PMID： 19853156     DOI： 10.1016/j.athoracsur.2009.05.079

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN： 0003-4975            Impact factor:   4.330


  14 in total

Review 1.  Control of autocrine and paracrine myocardial signals: an emerging therapeutic strategy in heart failure.

Authors:  Vincenzo Lionetti; Giacomo Bianchi; Fabio A Recchia; Carlo Ventura
Journal:  Heart Fail Rev       Date:  2010-11       Impact factor: 4.214

2.  Functionalized scaffold-mediated interleukin 10 gene delivery significantly improves survival rates of stem cells in vivo.

Authors:  Carolyn Holladay; Karen Power; Michael Sefton; Timothy O'Brien; William M Gallagher; Abhay Pandit
Journal:  Mol Ther       Date:  2011-01-25       Impact factor: 11.454

3.  Cardiac differentiation of cardiosphere-derived cells in scaffolds mimicking morphology of the cardiac extracellular matrix.

Authors:  Yanyi Xu; Sourav Patnaik; Xiaolei Guo; Zhenqing Li; Wilson Lo; Ryan Butler; Andrew Claude; Zhenguo Liu; Ge Zhang; Jun Liao; Peter M Anderson; Jianjun Guan
Journal:  Acta Biomater       Date:  2014-04-24       Impact factor: 8.947

Review 4.  Stem cell-based cardiac tissue engineering.

Authors:  Sara S Nunes; Hannah Song; C Katherine Chiang; Milica Radisic
Journal:  J Cardiovasc Transl Res       Date:  2011-07-12       Impact factor: 4.132

Review 5.  Role of molecular imaging in stem cell therapy for myocardial restoration.

Authors:  Maarten A Lijkwan; Ernst Jan Bos; Joseph C Wu; Robert C Robbins
Journal:  Trends Cardiovasc Med       Date:  2010-08       Impact factor: 6.677

6.  Comparison of cardiac stem cells and mesenchymal stem cells transplantation on the cardiac electrophysiology in rats with myocardial infarction.

Authors:  Shao-Xin Zheng; Yin-Lun Weng; Chang-Qing Zhou; Zhu-Zhi Wen; Hui Huang; Wei Wu; Jing-Feng Wang; Tong Wang
Journal:  Stem Cell Rev Rep       Date:  2013-06       Impact factor: 5.739

7.  Cell and gene therapies: moving from research to clinic.

Authors:  David F Stroncek; Raj K Puri
Journal:  J Transl Med       Date:  2010-03-29       Impact factor: 5.531

8.  Microfluidic artificial "vessels" for dynamic mechanical stimulation of mesenchymal stem cells.

Authors:  Jing Zhou; Laura E Niklason
Journal:  Integr Biol (Camb)       Date:  2012-12       Impact factor: 2.192

Review 9.  Molecular pathogenesis of myocardial remodeling and new potential therapeutic targets in chronic heart failure.

Authors:  Giuseppe Distefano; Pietro Sciacca
Journal:  Ital J Pediatr       Date:  2012-09-12       Impact factor: 2.638

10.  Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model.

Authors:  Emerson C Perin; Mei Tian; Frank C Marini; Guilherme V Silva; Yi Zheng; Fred Baimbridge; Xin Quan; Marlos R Fernandes; Amir Gahremanpour; Daniel Young; Vincenzo Paolillo; Uday Mukhopadhyay; Agatha T Borne; Rajesh Uthamanthil; David Brammer; James Jackson; William K Decker; Amer M Najjar; Michael W Thomas; Andrei Volgin; Brian Rabinovich; Suren Soghomonyan; Hwan-Jeong Jeong; Jesse M Rios; David Steiner; Simon Robinson; Osama Mawlawi; Tinsu Pan; Jason Stafford; Vikas Kundra; Chun Li; Mian M Alauddin; James T Willerson; Elizabeth Shpall; Juri G Gelovani
Journal:  PLoS One       Date:  2011-09-01       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.