The catecholamine neuron: Historical and future perspectives.

My goals for this perspective are to enumerate what I consider to have been the major discoveries in the investigations of the central catecholamine neuron systems from the synaptic, cellular and systems physiological and neurohistochemical perspectives. To do so, I will emphasize here the synaptic and physiological aspects of the central noradrenergic (NE) system, considering both the past research and what we may expect to witness in the decades ahead. Copyright 2009 Elsevier Ltd. All rights reserved.