Literature DB >> 1984840

c-myc and K-ras-2 oncogenes in B-cell chronic lymphocytic leukemia with del(12)(p13).

T Y Wang1, D M Samples, R Dabdoub, O Prakash.   

Abstract

Molecular and cytogenetic analyses were performed on chronic B-lymphocytic cell leukemia (CLL) from a 57-year-old male patient with del(12)(p13) anomaly. The deletion did not remove the K-ras-2 gene. However, c-myc gene amplification correlated with high-level expression, suggesting the involvement of this gene in the induction of neoplasia in this patient.

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Year:  1991        PMID: 1984840     DOI: 10.1016/0165-4608(91)90018-p

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  2 in total

1.  Case of chronic lymphocytic leukemia with unusual chromosome aberrations.

Authors:  Hui-Hua Hsiao; Yi-Hui Hung; Hui-Pin Hsiao; Shih-Bin Tseng; Hui-Jen Tsai; Yi-Chang Liu; Ta-Chih Liu; Mei-Chyn Chao; Yuli Chang; Sheng-Fung Lin
Journal:  Int J Hematol       Date:  2004-11       Impact factor: 2.490

Review 2.  Genetic alterations in chronic lymphocytic leukaemia.

Authors:  Llorenç Coll-Mulet; Joan Gil
Journal:  Clin Transl Oncol       Date:  2009-04       Impact factor: 3.405

  2 in total

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