Literature DB >> 15615260

Case of chronic lymphocytic leukemia with unusual chromosome aberrations.

Hui-Hua Hsiao1, Yi-Hui Hung, Hui-Pin Hsiao, Shih-Bin Tseng, Hui-Jen Tsai, Yi-Chang Liu, Ta-Chih Liu, Mei-Chyn Chao, Yuli Chang, Sheng-Fung Lin.   

Abstract

Chronic lymphocytic leukemia is one of the most common leukemias in the western world and consists of many chromosome aberrations. We report the case of a 74-year-old male patient with chronic lymphocytic leukemia with complex variant translocations t(8;22)(q24;q11) and der(8)t(6;8)(p21;p21) identified by chromosome banding analysis and confirmed by fluorescence in situ hybridization analysis of interphase cells. Because of the rarity of these changes, possible molecular mechanisms associated with this karyotype are discussed.

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Year:  2004        PMID： 15615260     DOI： 10.1532/ijh97.a10323

Source DB:  PubMed          Journal:  Int J Hematol        ISSN： 0925-5710            Impact factor:   2.490


  13 in total

1.  Unusual breakpoint distribution of 8p abnormalities in T-prolymphocytic leukemia: a study with YACS mapping to 8p11-p12.

Authors:  A Sorour; V Brito-Babapulle; D Smedley; M Yuille; D Catovsky
Journal:  Cancer Genet Cytogenet       Date:  2000-09

Review 2.  Chronic lymphocytic leukemia.

Authors:  Neil E Kay; Terry J Hamblin; Diane F Jelinek; Gordon W Dewald; John C Byrd; Sherif Farag; Margaret Lucas; Thomas Lin
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2002

3.  Aberrations of chromosome 6 in 193 newly diagnosed untreated cases of chronic lymphocytic leukemia.

Authors:  P Philip; C Geisler; M M Hansen; H Hasselbalch; B E Christensen; A Drivsholm; B Lund; J B Nielsen; K B Jensen; E Andersen
Journal:  Cancer Genet Cytogenet       Date:  1991-05

4.  c-myc and K-ras-2 oncogenes in B-cell chronic lymphocytic leukemia with del(12)(p13).

Authors:  T Y Wang; D M Samples; R Dabdoub; O Prakash
Journal:  Cancer Genet Cytogenet       Date:  1991-01

5.  Abnormalities of chromosome band 8p11 in leukemia: two clinical syndromes can be distinguished on the basis of MOZ involvement.

Authors:  R C Aguiar; A Chase; S Coulthard; D H Macdonald; M Carapeti; A Reiter; J Sohal; A Lennard; J M Goldman; N C Cross
Journal:  Blood       Date:  1997-10-15       Impact factor: 22.113

6.  Comparative genomic hybridization in chronic B-cell leukemias shows a high incidence of chromosomal gains and losses.

Authors:  M Bentz; K Huck; S du Manoir; S Joos; C A Werner; K Fischer; H Döhner; P Lichter
Journal:  Blood       Date:  1995-06-15       Impact factor: 22.113

Review 7.  Molecular biology of Burkitt's lymphoma.

Authors:  J L Hecht; J C Aster
Journal:  J Clin Oncol       Date:  2000-11-01       Impact factor: 44.544

8.  Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities.

Authors:  G Juliusson; D G Oscier; M Fitchett; F M Ross; G Stockdill; M J Mackie; A C Parker; G L Castoldi; A Guneo; S Knuutila; E Elonen; G Gahrton
Journal:  N Engl J Med       Date:  1990-09-13       Impact factor: 91.245

Review 9.  Chromosome aberrations in B-cell chronic lymphocytic leukemia: reassessment based on molecular cytogenetic analysis.

Authors:  H Döhner; S Stilgenbauer; K Döhner; M Bentz; P Lichter
Journal:  J Mol Med (Berl)       Date:  1999-02       Impact factor: 4.599

10.  Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in the t(8;13)(p11;q12) myeloproliferative syndrome.

Authors:  A Reiter; J Sohal; S Kulkarni; A Chase; D H Macdonald; R C Aguiar; C Gonçalves; J M Hernandez; B A Jennings; J M Goldman; N C Cross
Journal:  Blood       Date:  1998-09-01       Impact factor: 22.113
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  1 in total

1.  The clinical significance of 8q24/MYC rearrangement in chronic lymphocytic leukemia.

Authors:  Yan Li; Shimin Hu; Sa A Wang; Shaoying Li; Yang O Huh; Zhenya Tang; L Jeffrey Medeiros; Guilin Tang
Journal:  Mod Pathol       Date:  2016-02-26       Impact factor: 7.842
  1 in total

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