OBJECTIVES: Depression is associated with high healthcare utilization and related costs. Effective treatments might reduce the economic burden. The objective of this study was to establish the cost-utility of a minimal psychological intervention (MPI) aimed at reducing depression and improving quality of life in elderly persons with diabetes or chronic obstructive pulmonary disease and co-occurring minor, mild, or moderate depression. METHODS: Trial-based cost-utility analysis was used to compare the MPI with usual care. Annual costs and quality-adjusted life-years (QALYs) based on the Euroqol (EQ5D) and on depression-free days were calculated. RESULTS:Annual costs and effects were not significantly different for the MPI group and care as usual. Bootstrap analysis indicated a dominant intervention, with a probability of 63 percent that the MPI is less costly and more effective than usual care. CONCLUSIONS: The cost-effectiveness analysis does not support dissemination of the MPI in its current form. The economic evaluation study showed limited probability that MPI is cost-effective over usual care. Further adjustments to the MPI are needed to make the intervention suitable for dissemination in regular care. TRIAL REGISTRATION: isrctn.org, identifier: ISRCTN92331982.
RCT Entities:
OBJECTIVES:Depression is associated with high healthcare utilization and related costs. Effective treatments might reduce the economic burden. The objective of this study was to establish the cost-utility of a minimal psychological intervention (MPI) aimed at reducing depression and improving quality of life in elderly persons with diabetes or chronic obstructive pulmonary disease and co-occurring minor, mild, or moderate depression. METHODS: Trial-based cost-utility analysis was used to compare the MPI with usual care. Annual costs and quality-adjusted life-years (QALYs) based on the Euroqol (EQ5D) and on depression-free days were calculated. RESULTS: Annual costs and effects were not significantly different for the MPI group and care as usual. Bootstrap analysis indicated a dominant intervention, with a probability of 63 percent that the MPI is less costly and more effective than usual care. CONCLUSIONS: The cost-effectiveness analysis does not support dissemination of the MPI in its current form. The economic evaluation study showed limited probability that MPI is cost-effective over usual care. Further adjustments to the MPI are needed to make the intervention suitable for dissemination in regular care. TRIAL REGISTRATION: isrctn.org, identifier: ISRCTN92331982.
Authors: Katerina Papageorgiou; Karin M Vermeulen; Maya J Schroevers; Anne M Stiggelbout; Erik Buskens; Paul F M Krabbe; Edwin van den Heuvel; Adelita V Ranchor Journal: Qual Life Res Date: 2015-06-03 Impact factor: 4.147
Authors: Katerina Papageorgiou; Karin M Vermeulen; Maya J Schroevers; Erik Buskens; Adelita V Ranchor Journal: Health Qual Life Outcomes Date: 2013-07-26 Impact factor: 3.186
Authors: Anneke van Dijk-de Vries; Marloes A van Bokhoven; Berend Terluin; Trudy van der Weijden; Jacques Th M van Eijk Journal: BMC Fam Pract Date: 2013-06-07 Impact factor: 2.497