Literature DB >> 19844616

Thoracic myelopathy caused by ossification of the ligamentum flavum.

Hyuk Hur1, Jung-Kil Lee, Jae-Hyun Lee, Jae-Hyoo Kim, Soo-Han Kim.   

Abstract

OBJECTIVE: Ossification of the ligamentum flavum (OLF) is a rare cause of thoracic myelopathy. The aim of this study was to identify factors associated with the surgical outcome on the basis of preoperative clinical and radiological findings.
METHODS: Data obtained in 26 patients whot underwent posterior decompression for thoracic myelopathy, caused by thoracic OLF, were analyzed retrospectively. Patient age, duration of symptoms, OLF type, preoperative and postoperative neurological status using the Japanese Orthopedic Association (JOA) scoring system, surgical outcome, and other factors were reviewed. We compared the various factors and postoperative prognosis. All patients had undergone decompressive laminectomy and excision of the OLF.
RESULTS: Using the JOA score, the functional improvement was excellent in 8 patients, good in 14, fair in 2, and unchanged in 2. A mean preoperative JOA score of 6.65 improved to 8.17 after an average of 27.3 months. According to our analysis, age, gender, duration of symptoms, the involved spinal level, coexisting spinal disorders, associated trauma, intramedullary signal change, and dural adhesions were not related to the surgical outcome. However, the preoperative JOA score and type of OLF were the most important predictors of the surgical outcome.
CONCLUSION: Early diagnosis and sufficient surgical decompression could improve the functional prognosis for thoracic OLF. The postoperative results were found to be significantly associated with the preoperative severity of myelopathy and type of OLF.

Entities:  

Keywords:  Ossification of ligamentum flavum; Surgical outcome; Thoracic myelopathy

Year:  2009        PMID: 19844616      PMCID: PMC2764014          DOI: 10.3340/jkns.2009.46.3.189

Source DB:  PubMed          Journal:  J Korean Neurosurg Soc        ISSN: 1225-8245


  18 in total

1.  Surgical treatment for thoracic spinal stenosis.

Authors:  U K Chang; W J Choe; C K Chung; H J Kim
Journal:  Spinal Cord       Date:  2001-07       Impact factor: 2.772

2.  Expression and localization of bone morphogenetic proteins (BMPs) and BMP receptors in ossification of the ligamentum flavum.

Authors:  K Hayashi; Y Ishidou; K Yonemori; T Nagamine; N Origuchi; S Maeda; T Imamura; M Kato; H Yoshida; T K Sampath; P ten Dijke; T Sakou
Journal:  Bone       Date:  1997-07       Impact factor: 4.398

3.  Experimental chronic compression on the spinal cord of the rabbit by ectopic bone formation in the ligamentum flavum with bone morphogenetic protein.

Authors:  K Mimatsu; S Kishi; Y Hashizume
Journal:  Spinal Cord       Date:  1997-11       Impact factor: 2.772

4.  Symptomatic ossification of the ligamentum flavum: a clinical series from the French Antilles.

Authors:  Hugues Pascal-Moussellard; Philippe Cabre; Didier Smadja; Yves Catonné
Journal:  Spine (Phila Pa 1976)       Date:  2005-07-15       Impact factor: 3.468

5.  Spinal compression due to ossified yellow ligament: a short series of 5 patients and literature review.

Authors:  Sandeep Mohindra; Rajesh Chhabra; Kanchan Kumar Mukherjee; Sunil Kumar Gupta; Kim Vaiphei; Virender Kumar Khosla
Journal:  Surg Neurol       Date:  2006-04

6.  Elevated plasma fibronectin concentrations in patients with ossification of the posterior longitudinal ligament and ossification of the ligamentum flavum.

Authors:  S Miyamoto; K Yonenobu; K Ono
Journal:  Spine (Phila Pa 1976)       Date:  1993-11       Impact factor: 3.468

7.  Factors related to long-term outcome after decompressive surgery for ossification of the ligamentum flavum of the thoracic spine.

Authors:  Naohisa Miyakoshi; Yoichi Shimada; Tetsuya Suzuki; Michio Hongo; Yuji Kasukawa; Kyoji Okada; Eiji Itoi
Journal:  J Neurosurg       Date:  2003-10       Impact factor: 5.115

8.  Surgical outcome of thoracic myelopathy secondary to ossification of ligamentum flavum.

Authors:  Byung-Chul Park; Woo-Kie Min; Chang-Wug Oh; In-Ho Jeon; Shin-Yoon Kim; Hee-Soo Kyung; Soo-Hoon Oh
Journal:  Joint Bone Spine       Date:  2007-08-03       Impact factor: 4.929

9.  Thoracic myelopathy due to isolated ossification of the ligamentum flavum.

Authors:  T Shiraishi; H V Crock; P Lewis
Journal:  J Bone Joint Surg Br       Date:  1995-01

10.  Thoracic myelopathy caused by ossification of the ligamentum flavum: a report of 18 cases.

Authors:  Karim Ben Hamouda; Hafedh Jemel; Slim Haouet; Moncef Khaldi
Journal:  J Neurosurg       Date:  2003-09       Impact factor: 5.115

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  16 in total

1.  Thoracic myelopathy due to ossification of ligamentum flavum: a retrospective analysis of predictors of surgical outcome and factors affecting preoperative neurological status.

Authors:  Amish V Sanghvi; Harvinder Singh Chhabra; Amrithlal A Mascarenhas; Vivek K Mittal; Gururaj M Sangondimath
Journal:  Eur Spine J       Date:  2010-05-15       Impact factor: 3.134

2.  Design of mulitlevel OLF approach ("V"-shaped decompressive laminoplasty) based on 3D printing technology.

Authors:  Qinjie Ling; Erxing He; Hanbin Ouyang; Jing Guo; Zhixun Yin; Wenhua Huang
Journal:  Eur Spine J       Date:  2017-07-27       Impact factor: 3.134

3.  Clinical analysis of thoracic ossified ligamentum flavum without ventral compressive lesion.

Authors:  Sang Hoon Yoon; Wook Ha Kim; Sang-Bong Chung; Yong Jun Jin; Kun Woo Park; Joon Woo Lee; Sang-Ki Chung; Ki-Jeong Kim; Jin S Yeom; Tae-Ahn Jahng; Chun Kee Chung; Heung Sik Kang; Hyun-Jib Kim
Journal:  Eur Spine J       Date:  2010-07-14       Impact factor: 3.134

4.  Percutaneous full endoscopic posterior decompression of thoracic myelopathy caused by ossification of the ligamentum flavum.

Authors:  Bo An; Xing-Chen Li; Cheng-Pei Zhou; Bi-Sheng Wang; Hao-Ran Gao; Hai-Jun Ma; Yi He; Hong-Gang Zhou; He-Jun Yang; Ji-Xian Qian
Journal:  Eur Spine J       Date:  2019-01-17       Impact factor: 3.134

5.  Microendoscopic posterior decompression for the treatment of thoracic myelopathy caused by ossification of the ligamentum flavum: a technical report.

Authors:  Satoshi Baba; Yasushi Oshima; Tomoyuki Iwahori; Yuichi Takano; Hirohiko Inanami; Hisashi Koga
Journal:  Eur Spine J       Date:  2015-07-30       Impact factor: 3.134

6.  Clinical characteristics and surgical outcome of thoracic myelopathy caused by ossification of the ligamentum flavum: a retrospective analysis of 85 cases.

Authors:  Z Li; D Ren; Y Zhao; S Hou; L Li; S Yu; T Hou
Journal:  Spinal Cord       Date:  2015-08-04       Impact factor: 2.772

Review 7.  Outcomes and Complications Following Laminectomy Alone for Thoracic Myelopathy due to Ossified Ligamentum Flavum: A Systematic Review and Meta-Analysis.

Authors:  Nebiyu S Osman; Zoe B Cheung; Awais K Hussain; Kevin Phan; Varun Arvind; Khushdeep S Vig; Luilly Vargas; Jun S Kim; Samuel Kang-Wook Cho
Journal:  Spine (Phila Pa 1976)       Date:  2018-07-15       Impact factor: 3.241

8.  Predictors of surgical outcome in thoracic ossification of the ligamentum flavum: focusing on the quantitative signal intensity.

Authors:  JingTao Zhang; LinFeng Wang; Jie Li; Peng Yang; Yong Shen
Journal:  Sci Rep       Date:  2016-03-10       Impact factor: 4.379

9.  Ossification of the ligamentum flavum as cause of thoracic cord compression: Case report of a Latin American man and review of the literature.

Authors:  Javier A Toledo; Facundo Van Isseldyk; Martín Re; Miguel Garrote
Journal:  Surg Neurol Int       Date:  2013-09-19

10.  Isolated ligamentum flavum ossification in primary hypoparathyroidism.

Authors:  Amir H Sohail; Muhammad A A Maan; Muhammad S Khan; Qamar Masood
Journal:  Surg Neurol Int       Date:  2018-01-10
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