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Literature DB >> 19841645

The gut feeling of Treg cells: IL-10 is the silver lining during colitis.

Abstract

Regulatory T cells that express the transcription factor Foxp3 are pivotal in suppressing autoimmune responses. A report in this issue describes a key role for interleukin 10 produced by lamina propria macrophages in maintaining Foxp3 expression during inflammatory responses in the intestine.

Entities: Disease Gene

Mesh：

Substances：

Year: 2009 PMID： 19841645 DOI： 10.1038/ni1109-1141

Source DB: PubMed Journal: Nat Immunol ISSN： 1529-2908 Impact factor: 25.606

11 in total

1. IL-10 secretion and sensitivity in normal human intestine and inflammatory bowel disease.

Authors: C Gasche; S Bakos; C Dejaco; W Tillinger; S Zakeri; W Reinisch
Journal: J Clin Immunol Date: 2000-09 Impact factor: 8.317

Review 2. Regulatory T cells and immune tolerance.

Authors: Shimon Sakaguchi; Tomoyuki Yamaguchi; Takashi Nomura; Masahiro Ono
Journal: Cell Date: 2008-05-30 Impact factor: 41.582

Review 3. Role of cytokines in the pathogenesis of inflammatory bowel disease.

Authors: K A Papadakis; S R Targan
Journal: Annu Rev Med Date: 2000 Impact factor: 13.739

4. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses.

Authors: Timothy L Denning; Yi-chong Wang; Seema R Patel; Ifor R Williams; Bali Pulendran
Journal: Nat Immunol Date: 2007-09-16 Impact factor: 25.606

5. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces.

Authors: Yuri P Rubtsov; Jeffrey P Rasmussen; Emil Y Chi; Jason Fontenot; Luca Castelli; Xin Ye; Piper Treuting; Lisa Siewe; Axel Roers; William R Henderson; Werner Muller; Alexander Y Rudensky
Journal: Immunity Date: 2008-04 Impact factor: 31.745

6. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis.

Authors: Masako Murai; Olga Turovskaya; Gisen Kim; Rajat Madan; Christopher L Karp; Hilde Cheroutre; Mitchell Kronenberg
Journal: Nat Immunol Date: 2009-09-27 Impact factor: 25.606

Review 7. Interleukin-10-based therapy for inflammatory bowel disease.

Authors: Henri Braat; Maikel P Peppelenbosch; Daan W Hommes
Journal: Expert Opin Biol Ther Date: 2003-08 Impact factor: 4.388

Review 8. Plasticity of CD4(+) FoxP3(+) T cells.

Authors: Xuyu Zhou; Samantha Bailey-Bucktrout; Lukas T Jeker; Jeffrey A Bluestone
Journal: Curr Opin Immunol Date: 2009-06-06 Impact factor: 7.486

9. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells.

Authors: Julien C Marie; John J Letterio; Marc Gavin; Alexander Y Rudensky
Journal: J Exp Med Date: 2005-04-04 Impact factor: 14.307

10. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.

Authors: Xuyu Zhou; Samantha L Bailey-Bucktrout; Lukas T Jeker; Cristina Penaranda; Marc Martínez-Llordella; Meredith Ashby; Maki Nakayama; Wendy Rosenthal; Jeffrey A Bluestone
Journal: Nat Immunol Date: 2009-07-26 Impact factor: 25.606

17 in total

Review 1. M cell-targeted mucosal vaccine strategies.

Authors: M Yamamoto; D W Pascual; H Kiyono
Journal: Curr Top Microbiol Immunol Date: 2012 Impact factor: 4.291

2. A transgenic probiotic secreting a parasite immunomodulator for site-directed treatment of gut inflammation.

Authors: Rose A Whelan; Sebastian Rausch; Friederike Ebner; Dorothee Günzel; Jan F Richter; Nina A Hering; Jörg-Dieter Schulzke; Anja A Kühl; Ahmed Keles; Pawel Janczyk; Karsten Nöckler; Lothar H Wieler; Susanne Hartmann
Journal: Mol Ther Date: 2014-07-02 Impact factor: 11.454

Review 3. Intestinal dendritic cells in the pathogenesis of inflammatory bowel disease.

Authors: Sergio Rutella; Franco Locatelli
Journal: World J Gastroenterol Date: 2011-09-07 Impact factor: 5.742

Review 4. Animal models of inflammatory bowel disease: a review.

Authors: Nidhi Goyal; Ajay Rana; Abhilasha Ahlawat; Krishna Reddy V Bijjem; Puneet Kumar
Journal: Inflammopharmacology Date: 2014-06-07 Impact factor: 4.473

5. Effect of resveratrol on Treg/Th17 signaling and ulcerative colitis treatment in mice.

Authors: Jun Yao; Cheng Wei; Jian-Yao Wang; Ru Zhang; Ying-Xue Li; Li-Sheng Wang
Journal: World J Gastroenterol Date: 2015-06-07 Impact factor: 5.742

6. Targeting IL-12/IL-23 by employing a p40 peptide-based vaccine ameliorates TNBS-induced acute and chronic murine colitis.

Authors: Qingdong Guan; Yanbing Ma; China-Li Hillman; Gefei Qing; Allan G Ma; Carolyn R Weiss; Gang Zhou; Aiping Bai; Richard J Warrington; Charles N Bernstein; Zhikang Peng
Journal: Mol Med Date: 2011-03-11 Impact factor: 6.354

7. Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine.

Authors: Tania Konry; Margarita Dominguez-Villar; Clare Baecher-Allan; David A Hafler; Martin L Yarmush
Journal: Biosens Bioelectron Date: 2010-09-15 Impact factor: 10.618

8. Epigallocatechin-3-gallate-induced inhibition of interleukin-6 release and adjustment of the regulatory T/T helper 17 cell balance in the treatment of colitis in mice.

Authors: Zhenglei Xu; Cheng Wei; R U Zhang; Jun Yao; Dinguo Zhang; Lisheng Wang
Journal: Exp Ther Med Date: 2015-10-23 Impact factor: 2.447

9. Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers.

Authors: Ian Teo; Steve M Toms; Benoit Marteyn; Teresa S Barata; Peter Simpson; Karen A Johnston; Pamela Schnupf; Andrea Puhar; Tracey Bell; Chris Tang; Mire Zloh; Steve Matthews; Phillip M Rendle; Philippe J Sansonetti; Sunil Shaunak
Journal: EMBO Mol Med Date: 2012-08-06 Impact factor: 12.137

10. Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.

Authors: Lingjun Tong; Haining Hao; Zhe Zhang; Youyou Lv; Xi Liang; Qiqi Liu; Tongjie Liu; Pimin Gong; Lanwei Zhang; Fangfang Cao; Giorgia Pastorin; Chuen Neng Lee; Xiaoyuan Chen; Jiong-Wei Wang; Huaxi Yi
Journal: Theranostics Date: 2021-07-25 Impact factor: 11.556