Literature DB >> 19840543

Harnessing immune alterations in neurodegenerative diseases.

Maria Björkqvist1, Edward J Wild, Sarah J Tabrizi.   

Abstract

Immune dysfunction, a well-established feature of neuroinflammatory disease, is increasingly recognized in neurodegenerative conditions. Its role is emerging as an early and active participant in neuropathology. Inflammation could be modified, with disease-slowing effects, by targeted interventions; it is also readily detectable and could serve as a source of valuable biomarkers.

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Year:  2009        PMID： 19840543     DOI： 10.1016/j.neuron.2009.09.034

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  20 in total

Review 1.  Huntington disease: natural history, biomarkers and prospects for therapeutics.

Authors:  Christopher A Ross; Elizabeth H Aylward; Edward J Wild; Douglas R Langbehn; Jeffrey D Long; John H Warner; Rachael I Scahill; Blair R Leavitt; Julie C Stout; Jane S Paulsen; Ralf Reilmann; Paul G Unschuld; Alice Wexler; Russell L Margolis; Sarah J Tabrizi
Journal:  Nat Rev Neurol       Date:  2014-03-11       Impact factor: 42.937

2.  Beneficial effects of glatiramer acetate in Huntington's disease mouse models: Evidence for BDNF-elevating and immunomodulatory mechanisms.

Authors:  Jody Corey-Bloom; Alaina M Aikin; Ashley M Gutierrez; Jwan S Nadhem; Taylor L Howell; Elizabeth A Thomas
Journal:  Brain Res       Date:  2017-08-18       Impact factor: 3.252

Review 3.  Peripheral inflammation in neurodegeneration.

Authors:  Ulrike Träger; Sarah J Tabrizi
Journal:  J Mol Med (Berl)       Date:  2013-04-02       Impact factor: 4.599

4.  Protective Effect of Lupeol Against Lipopolysaccharide-Induced Neuroinflammation via the p38/c-Jun N-Terminal Kinase Pathway in the Adult Mouse Brain.

Authors:  Haroon Badshah; Tahir Ali; Faheem Ullah; Tae Hyun Kim; Myeong Ok Kim
Journal:  J Neuroimmune Pharmacol       Date:  2015-07-03       Impact factor: 4.147

Review 5.  Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis.

Authors:  C Y Daniel Lee; Jeffrey P Cantle; X William Yang
Journal:  FEBS J       Date:  2013-07-31       Impact factor: 5.542

6.  Serum levels of a subset of cytokines show high interindividual variability and are not altered in rats transgenic for Huntington´s disease.

Authors:  Huu Phuc Nguyen; Maria Björkqvist; Felix J Bode; Michael Stephan; Stephan von Hörsten
Journal:  PLoS Curr       Date:  2010-10-21

7.  RAN Translation in Huntington Disease.

Authors:  Monica Bañez-Coronel; Fatma Ayhan; Alex D Tarabochia; Tao Zu; Barbara A Perez; Solaleh Khoramian Tusi; Olga Pletnikova; David R Borchelt; Christopher A Ross; Russell L Margolis; Anthony T Yachnis; Juan C Troncoso; Laura P W Ranum
Journal:  Neuron       Date:  2015-11-18       Impact factor: 17.173

8.  Abnormal peripheral chemokine profile in Huntington's disease.

Authors:  Edward Wild; Anna Magnusson; Nayana Lahiri; Ulrika Krus; Michael Orth; Sarah J Tabrizi; Maria Björkqvist
Journal:  PLoS Curr       Date:  2011-04-13

9.  Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens.

Authors:  Stephanie C Joachim; Oliver W Gramlich; Panagiotis Laspas; Heiko Schmid; Sabine Beck; Harald D von Pein; H Burkhard Dick; Norbert Pfeiffer; Franz H Grus
Journal:  PLoS One       Date:  2012-07-26       Impact factor: 3.240

Review 10.  Microglial cell dysregulation in brain aging and neurodegeneration.

Authors:  Rommy von Bernhardi; Laura Eugenín-von Bernhardi; Jaime Eugenín
Journal:  Front Aging Neurosci       Date:  2015-07-20       Impact factor: 5.750
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