Literature DB >> 19839151

Nasopharyngeal carcinoma: a delay in diagnosis.

U Prasad1, K C Pua.   

Abstract

One hundred consecutive newly diagnosed patients with nasopharyngeal carcinoma (NPC) since January 1994 were the subjects for studying various factors that contribute to the delay in the confirmation of the diagnosis. Seventy-nine of them were males and the peak age of incidence was the fifth decade. Ninety two percent were Chinese, 7% Malay and 1% Indian. Seventy six percent were agriculture workers or labourers with 66% having either no formal education (16%) or only primary level education (50%). In 50% of patients neck swelling was the first presenting symptom, 26% had nasal symptoms, 12% ear symptoms and 11% has symptoms due to intracranial extension of tumour. As many as 80% were at UICC Stage IV at the time of diagnosis. While the median delay, on the part of patients, in consulting a doctor was 2.5 days, the median delay on the part of the doctors to confirm the diagnosis of NPC was 127 days, the delays was particularly worse when the patients presented with ear symptoms (266 days) followed by those with neck swelling (94 days). For those patients who were required to undergo more than one nasopharyngoscopy and biopsy the median doctor's delay was 144 days. Since 82% of patient's had first consulted general practitioners, it is suggested that their level of awareness with regards to the diagnosis of NPC be significantly raised so that the delay on their part be greatly minimized.

Entities:  

Mesh:

Year:  2000        PMID: 19839151

Source DB:  PubMed          Journal:  Med J Malaysia        ISSN: 0300-5283


  11 in total

1.  Exploring the knowledge of nasopharyngeal carcinoma among medical doctors at primary health care level in Perak state, Malaysia.

Authors:  Rekha Balachandran; Rajan Philip; Singh Avatar; Rosalind Simon; Gurdeep Singh Mann; Chong Tak Wai Benedict; Chong Ai Ling Amy; May Lee Ch'ng
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-06-21       Impact factor: 2.503

2.  Epstein-Barr virus Latent Membrane Protein LMP1 reduces p53 protein levels independent of the PI3K-Akt pathway.

Authors:  Roslina Husaini; Munirah Ahmad; Alan Soo-Beng Khoo
Journal:  BMC Res Notes       Date:  2011-12-21

3.  Short-term effect of different teaching methods on nasopharyngeal carcinoma for general practitioners in Jakarta, Indonesia.

Authors:  Maarten A Wildeman; Renske Fles; Marlinda Adham; Ika D Mayangsari; Ilse Luirink; Mara Sandberg; Andrew D Vincent; Faiziah Fardizza; Zanil Musa; Jaap M Middeldorp; Geerten Gerritsen; Ronny Suwanto; I Bing Tan
Journal:  PLoS One       Date:  2012-03-14       Impact factor: 3.240

4.  Distinctive microRNA expression in early stage nasopharyngeal carcinoma patients.

Authors:  Shuna Li; Lihua Hang; Yongming Ma; Chaoyang Wu
Journal:  J Cell Mol Med       Date:  2016-08-04       Impact factor: 5.310

5.  The role of Indonesian patients' health behaviors in delaying the diagnosis of nasopharyngeal carcinoma.

Authors:  R Fles; A C R K Bos; D Rachmawati; E Waliyanti; I B Tan; S M Haryana; M K Schmidt; F S T Dewi
Journal:  BMC Public Health       Date:  2017-05-25       Impact factor: 3.295

6.  Nasopharyngeal Carcinoma: A Retrospective Study on Imaging Patterns at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.

Authors:  Amal Saleh Nour; Tequam Debebe Weldehawariat; Aynalem Abraha Woldemariam; Dheresa Gelana Layo
Journal:  Ethiop J Health Sci       Date:  2020-03

7.  Survival outcome and prognostic factors of patients with nasopharyngeal cancer in Yogyakarta, Indonesia: A hospital-based retrospective study.

Authors:  Susanna Hilda Hutajulu; Daniel Howdon; Kartika Widayati Taroeno-Hariadi; Mardiah Suci Hardianti; Ibnu Purwanto; Sagung Rai Indrasari; Camelia Herdini; Bambang Hariwiyanto; Ahmad Ghozali; Henry Kusumo; Wigati Dhamiyati; Sri Retna Dwidanarti; I Bing Tan; Johan Kurnianda; Matthew John Allsop
Journal:  PLoS One       Date:  2021-02-12       Impact factor: 3.240

8.  Primary treatment results of Nasopharyngeal Carcinoma (NPC) in Yogyakarta, Indonesia.

Authors:  Maarten A Wildeman; Renske Fles; Camelia Herdini; Rai S Indrasari; Andrew D Vincent; Maesadji Tjokronagoro; Sharon Stoker; Johan Kurnianda; Baris Karakullukcu; Kartika W Taroeno-Hariadi; Olga Hamming-Vrieze; Jaap M Middeldorp; Bambang Hariwiyanto; Sofia M Haryana; I Bing Tan
Journal:  PLoS One       Date:  2013-05-10       Impact factor: 3.240

9.  Effectiveness of a multicentre nasopharyngeal carcinoma awareness programme in Indonesia.

Authors:  Renske Fles; Sagung R Indrasari; Camelia Herdini; Santi Martini; Atoillah Isfandiari; Achmad C Romdhoni; Marlinda Adham; Ika D Mayangsari; Erik van Werkhoven; Maarten A Wildeman; Bambang Hariwiyanto; Bambang Hermani; Widodo A Kentjono; Sofia M Haryana; Marjanka K Schmidt; I Bing Tan
Journal:  BMJ Open       Date:  2016-03-01       Impact factor: 2.692

10.  Prognostic factors of nasopharyngeal carcinoma patients in a tertiary referral hospital: a retrospective cohort study.

Authors:  Ab Hamid Siti-Azrin; Bachok Norsa'adah; Nyi Nyi Naing
Journal:  BMC Res Notes       Date:  2017-12-06
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