Literature DB >> 19833574

DNA distress: just ring 9-1-1.

Michael Kemp1, Aziz Sancar.   

Abstract

The Rad9-Hus1-Rad1 checkpoint clamp (9-1-1) is a central player in the cellular response to DNA damage; three groups have determined the crystal structure of 9-1-1, providing new insight into its loading mechanism and association with DNA damage checkpoint and repair enzymes.

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Year:  2009        PMID: 19833574     DOI: 10.1016/j.cub.2009.07.026

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  6 in total

Review 1.  The role of RAD9 in tumorigenesis.

Authors:  Howard B Lieberman; Joshua D Bernstock; Constantinos G Broustas; Kevin M Hopkins; Corinne Leloup; Aiping Zhu
Journal:  J Mol Cell Biol       Date:  2011-02       Impact factor: 6.216

2.  RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling.

Authors:  Laura A Lindsey-Boltz; Michael G Kemp; Christopher Capp; Aziz Sancar
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

3.  Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1.

Authors:  Gabriel Balmus; Min Zhu; Sucheta Mukherjee; Amy M Lyndaker; Kelly R Hume; Jaesung Lee; Mark L Riccio; Anthony P Reeves; Nathan B Sutter; Drew M Noden; Rachel M Peters; Robert S Weiss
Journal:  Hum Mol Genet       Date:  2012-05-09       Impact factor: 6.150

4.  ZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline.

Authors:  Hyun-Min Kim; Monica P Colaiácovo
Journal:  PLoS Genet       Date:  2014-10-16       Impact factor: 5.917

5.  p53 and cyclin G cooperate in mediating genome stability in somatic cells of Drosophila.

Authors:  Fabienne E Bayer; Mirjam Zimmermann; Patrick Fischer; Christian Gromoll; Anette Preiss; Anja C Nagel
Journal:  Sci Rep       Date:  2017-12-20       Impact factor: 4.379

6.  Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress.

Authors:  M D Wallace; T L Southard; K J Schimenti; J C Schimenti
Journal:  Oncogene       Date:  2013-08-26       Impact factor: 9.867

  6 in total

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