BACKGROUND: The aim of this study was to evaluate changes in quality-of-life following laparoscopic cholecystectomy (LC) in adults with cholelithiasis. METHODS: Patients were evaluated with the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and the Gastrointestinal Quality of Life Index (GIQLI) preoperatively and 12 months after LC. Outcome predictors were analyzed using correlation and regression statistics. RESULTS: Ninety-nine patients were enrolled (male/female, 32:67, age 49.8 +/- 13.7 years old). At baseline, patients performed inferiorly to general population in all SF-36 general health dimensions (p < 0.0001). Postoperatively, the "role-physical", "role-emotional", and "bodily pain" dimensions of health significantly improved. There were significant improvements in GIQLI "total", "physical well-being", "mental well-being", "gastrointestinal digestion", and "defecation" subscales scores. Serum direct bilirubin level and drainage tube indwelling were significant predictors for quality-of-life improvement following LC. CONCLUSIONS: LC can greatly reduce gastrointestinal symptoms to improve quality-of-life for patients with cholelithiasis. Patients with severe baseline conditions may benefit from greater quality-of-life improvement following LC.
BACKGROUND: The aim of this study was to evaluate changes in quality-of-life following laparoscopic cholecystectomy (LC) in adults with cholelithiasis. METHODS:Patients were evaluated with the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and the Gastrointestinal Quality of Life Index (GIQLI) preoperatively and 12 months after LC. Outcome predictors were analyzed using correlation and regression statistics. RESULTS: Ninety-nine patients were enrolled (male/female, 32:67, age 49.8 +/- 13.7 years old). At baseline, patients performed inferiorly to general population in all SF-36 general health dimensions (p < 0.0001). Postoperatively, the "role-physical", "role-emotional", and "bodily pain" dimensions of health significantly improved. There were significant improvements in GIQLI "total", "physical well-being", "mental well-being", "gastrointestinal digestion", and "defecation" subscales scores. Serum direct bilirubin level and drainage tube indwelling were significant predictors for quality-of-life improvement following LC. CONCLUSIONS: LC can greatly reduce gastrointestinal symptoms to improve quality-of-life for patients with cholelithiasis. Patients with severe baseline conditions may benefit from greater quality-of-life improvement following LC.
Authors: Malte Schmidt; Karl Søndenaa; John A Dumot; Steven Rosenblatt; Trygve Hausken; Maria Ramnefjell; Gro Njølstad; Geir Egil Eide Journal: World J Gastroenterol Date: 2012-03-28 Impact factor: 5.742
Authors: Kimberly M Brown; B Todd Moore; G Brent Sorensen; Conrad H Boettger; Fengming Tang; Phil G Jones; Daniel J Margolin Journal: Surg Endosc Date: 2013-03-22 Impact factor: 4.584
Authors: Mark P Lamberts; Wietske Kievit; Jos J G M Gerritsen; Jan A Roukema; Gert P Westert; Joost P H Drenth; Cornelis J H M van Laarhoven Journal: J Gastrointest Surg Date: 2016-05-17 Impact factor: 3.452