Literature DB >> 19830193

Fixed drug eruption resulting from fluconazole use: a case report.

Mahkam Tavallaee, Mahnaz Mahmoudi Rad.   

Abstract

INTRODUCTION: Fluconazole is a widely used antifungal agent with a possible side effect of fixed drug eruption. However, this adverse drug effect is absent from the reported list of possible side effects of fluconazole. We are presenting a rare case in our report. CASE
PRESENTATION: A 25-year-old Iranian woman developed fixed drug eruptions on different sites of her body after taking five doses of fluconazole to treat vaginal candidiasis. A positive patch test, positive oral challenge test and skin biopsy were all found to be consistent with fixed drug eruption.
CONCLUSION: Fluconazole is a widely prescribed drug, used mainly to treat candidiasis. Fixed drug eruption as a possible side effect of Fluconazole is not well known and thus, the lesions may be misdiagnosed and mistreated. Based on our findings, which are consistent with a number of other practitioners, we recommend adding fixed drug eruption to the list of possible side effects of fluconazole.

Entities:  

Year:  2009        PMID: 19830193      PMCID: PMC2737765          DOI: 10.4076/1752-1947-3-7368

Source DB:  PubMed          Journal:  J Med Case Rep        ISSN: 1752-1947


  14 in total

1.  Fixed drug eruption due to fluconazole.

Authors:  H Heikkilä; K Timonen; S Stubb
Journal:  J Am Acad Dermatol       Date:  2000-05       Impact factor: 11.527

2.  Oral challenge in patients with suspected cutaneous adverse drug reactions: findings in 784 patients during a 25-year-period.

Authors:  Kaija Lammintausta; Outi Kortekangas-Savolainen
Journal:  Acta Derm Venereol       Date:  2005       Impact factor: 4.437

3.  Oral fixed drug eruption due to fluconazole.

Authors:  Aneet Mahendra; Sanjeev Gupta; Sunita Gupta; Shaveta Sood; Parveen Kumar
Journal:  Indian J Dermatol Venereol Leprol       Date:  2006 Sep-Oct       Impact factor: 2.545

4.  Fixed drug eruption of the vulva secondary to fluconazole.

Authors:  E M Wain; S Neill
Journal:  Clin Exp Dermatol       Date:  2008-08-02       Impact factor: 3.470

5.  A young woman with recurrent vesicles on the lower lip: fixed drug eruption mimicking herpes simplex.

Authors:  Frauke Benedix; Melany Schilling; Martin Schaller; Martin Röcken; Tilo Biedermann
Journal:  Acta Derm Venereol       Date:  2008       Impact factor: 4.437

6.  Drugs causing fixed eruptions: a study of 450 cases.

Authors:  A Mahboob; T S Haroon
Journal:  Int J Dermatol       Date:  1998-11       Impact factor: 2.736

7.  Fixed drug eruption with fluconazole.

Authors:  J M Morgan; A J Carmichael
Journal:  BMJ       Date:  1994-02-12

8.  Drug related involvement of specific sites in fixed eruptions: a statistical evaluation.

Authors:  V K Sharma; S Dhar; A N Gill
Journal:  J Dermatol       Date:  1996-08       Impact factor: 4.005

9.  Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study.

Authors:  Maja Mockenhaupt; Cecile Viboud; Ariane Dunant; Luigi Naldi; Sima Halevy; Jan Nico Bouwes Bavinck; Alexis Sidoroff; Jürgen Schneck; Jean-Claude Roujeau; Antoine Flahault
Journal:  J Invest Dermatol       Date:  2007-09-06       Impact factor: 8.551

10.  Topical provocation of fixed drug eruption. A study of 30 patients.

Authors:  K Alanko
Journal:  Contact Dermatitis       Date:  1994-07       Impact factor: 6.600

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  2 in total

1.  Fixed drug eruption due to fluconazole.

Authors:  Jennifer Beecker; Sophia Colantonio
Journal:  CMAJ       Date:  2012-01-09       Impact factor: 8.262

2.  Fixed drug eruption caused by fluconazole-An underdiagnosed but recurrent problem.

Authors:  Tamara Quint; Stefan Wöhrl; Tamar Kinaciyan
Journal:  Contact Dermatitis       Date:  2018-11-12       Impact factor: 6.600

  2 in total

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