Literature DB >> 19825488

Postoperative cognitive dysfunction in the elderly.

Ramesh Ramaiah1, Arthur M Lam.   

Abstract

Despite improvement in surgical techniques, anesthetic management, and intensive care, a significant number of elderly patients develop postoperative cognitive decline. Postoperative cognitive dysfunction (POCD) is a postoperative memory or thinking impairment that has been corroborated by neuropsychological testing, for which increasing age is the leading risk factor. POCD is multifactorial in origin, but it remains unclear whether its occurrence is a result of surgery or general anesthesia. This article discusses the incidence, assessment, consequences, and prevention of POCD, as well as anesthetic strategies to improve cognitive outcome in elderly patients.

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Year:  2009        PMID: 19825488     DOI: 10.1016/j.anclin.2009.07.011

Source DB:  PubMed          Journal:  Anesthesiol Clin        ISSN: 1932-2275


  31 in total

1.  Early postoperative delirium after open-heart cardiac surgery is associated with decreased bispectral EEG and increased cortisol and interleukin-6.

Authors:  Konstanze Plaschke; Philipp Fichtenkamm; Christoph Schramm; Steffen Hauth; Eike Martin; Markus Verch; Matthias Karck; Jürgen Kopitz
Journal:  Intensive Care Med       Date:  2010-08-06       Impact factor: 17.440

Review 2.  Brief review: anesthetic neurotoxicity in the elderly, cognitive dysfunction and Alzheimer's disease.

Authors:  Edward A Bittner; Yun Yue; Zhongcong Xie
Journal:  Can J Anaesth       Date:  2010-12-21       Impact factor: 5.063

3.  Resveratrol pretreatment attenuates the isoflurane-induced cognitive impairment through its anti-inflammation and -apoptosis actions in aged mice.

Authors:  Xiao-Min Li; Mai-Tao Zhou; Xing-Ming Wang; Mu-Huo Ji; Zhi-Qiang Zhou; Jian-Jun Yang
Journal:  J Mol Neurosci       Date:  2013-10-15       Impact factor: 3.444

4.  The relationship of cognitive performance to concurrent symptoms, cancer- and cancer-treatment-related variables in women with early-stage breast cancer: a 2-year longitudinal study.

Authors:  Debra E Lyon; Ronald Cohen; Huaihou Chen; Debra L Kelly; Angela Starkweather; Hyo-Chol Ahn; Colleen K Jackson-Cook
Journal:  J Cancer Res Clin Oncol       Date:  2016-04-21       Impact factor: 4.553

5.  Pervasive cognitive impairment in acute rehabilitation inpatients without brain injury.

Authors:  Adam J Woods; Victor W Mark; Anthony C Pitts; Mark Mennemeier
Journal:  PM R       Date:  2011-05       Impact factor: 2.298

6.  Prevalence of limited health literacy and compensatory strategies used by hospitalized patients.

Authors:  Nancy S Morris; Steven Grant; Allen Repp; Charles Maclean; Benjamin Littenberg
Journal:  Nurs Res       Date:  2011 Sep-Oct       Impact factor: 2.381

7.  Task-related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults.

Authors:  Jeffrey N Browndyke; Miles Berger; Patrick J Smith; Todd B Harshbarger; Zachary A Monge; Viral Panchal; Tiffany L Bisanar; Donald D Glower; John H Alexander; Roberto Cabeza; Kathleen Welsh-Bohmer; Mark F Newman; Joseph P Mathew
Journal:  Hum Brain Mapp       Date:  2017-11-21       Impact factor: 5.038

8.  Cognitive dysfunction with aging and the role of inflammation.

Authors:  Arthur A Simen; Kelly A Bordner; Mark P Martin; Lawrence A Moy; Lisa C Barry
Journal:  Ther Adv Chronic Dis       Date:  2011-05       Impact factor: 5.091

9.  Decrease in daytime sleeping is associated with improvement in cognition after hospital discharge in older adults.

Authors:  Joseph M Dzierzewski; Constance H Fung; Stella Jouldjian; Cathy A Alessi; Michael R Irwin; Jennifer L Martin
Journal:  J Am Geriatr Soc       Date:  2014-01-17       Impact factor: 5.562

Review 10.  Neurocognitive Adverse Effects of Anesthesia in Adults and Children: Gaps in Knowledge.

Authors:  Christopher G Ward; Roderic G Eckenhoff
Journal:  Drug Saf       Date:  2016-07       Impact factor: 5.606

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