| Literature DB >> 19819550 |
Mineshi Sakamoto1, Katsuyuki Murata, Machi Kubota, Kunihiko Nakai, Hiroshi Satoh.
Abstract
Mercury (Hg) and other heavy metal profiles, namely, lead (Pb), arsenic (As), cadmium (Cd), and selenium (Se) were investigated in maternal and umbilical cord (cord) red blood cells (RBCs) at parturition in Japanese population. Correlation coefficients of Hg, Pb, As, Cd, and Se between maternal and cord RBCs were 0.91, 0.79, 0.89, 0.31, and 0.76, respectively, and the respective means of cord/maternal RBCs ratios were 1.63, 0.52, 0.62, 0.12, and 1.18. These results indicate that fetal exposure to these metals (excluding Cd) strongly reflected each maternal exposure level. Among these metals, the placental transfer of methylmercury (MeHg) seemed to be extremely high but that of Cd to be limited. Hg showed positive correlations with Se in maternal RBCs but not in cord RBCs, and the Se/Hg molar ratio was lower in the latter, suggesting that the protective effects of Se against MeHg are less expected in fetuses than in mothers.Entities:
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Year: 2009 PMID： 19819550 DOI： 10.1016/j.ecoenv.2009.09.010
Source DB: PubMed Journal: Ecotoxicol Environ Saf ISSN： 0147-6513 Impact factor: 6.291