INTRODUCTION: The effects of blood donation on iron status in donors without iron supplementation were studied. Analysing interactions between donations and iron status markers may predict these effects. MATERIALS AND METHODS: Haemoglobin (Hb) and serum ferritin were analysed in 893 donors over 1 year. Serum transferrin receptor (sTfR) was measured at the first and last donation. RESULTS: Prolonged intervals prevented decrease in Hb in women and in ferritin for both genders. In women, a high TfR-F index (sTfR/log ferritin) predicted fall in Hb. CONCLUSION: Adjusting the donation intervals is a way to prevent iron deficiency in blood donors.
INTRODUCTION: The effects of blood donation on iron status in donors without iron supplementation were studied. Analysing interactions between donations and iron status markers may predict these effects. MATERIALS AND METHODS: Haemoglobin (Hb) and serum ferritin were analysed in 893 donors over 1 year. Serum transferrin receptor (sTfR) was measured at the first and last donation. RESULTS: Prolonged intervals prevented decrease in Hb in women and in ferritin for both genders. In women, a high TfR-F index (sTfR/log ferritin) predicted fall in Hb. CONCLUSION: Adjusting the donation intervals is a way to prevent iron deficiency in blood donors.
Authors: Ritchard G Cable; Simone A Glynn; Joseph E Kiss; Alan E Mast; Whitney R Steele; Edward L Murphy; David J Wright; Ronald A Sacher; Jerry L Gottschall; Leslie H Tobler; Toby L Simon Journal: Transfusion Date: 2011-10-24 Impact factor: 3.157
Authors: Joseph E Kiss; Whitney R Steele; David J Wright; Alan E Mast; Patricia M Carey; Edward L Murphy; Jerry L Gottschall; Toby L Simon; Ritchard G Cable Journal: Transfusion Date: 2013-04-26 Impact factor: 3.157