Literature DB >> 19815084

X inactivation and disease.

Ruben Agrelo1, Anton Wutz.   

Abstract

X inactivation is the mechanism by which mammals adjust the X-linked gene dosage between the sexes. The dosage difference between XX females and XY males is functionally equalized by silencing one of the two X chromosomes in female cells. This dosage-compensation mechanism is based on the long functional Xist RNA. Here, we review our understanding of dosage compensation and Xist function in the context of disease. Copyright 2009 Elsevier Ltd. All rights reserved.

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Year:  2009        PMID： 19815084     DOI： 10.1016/j.semcdb.2009.09.017

Source DB:  PubMed          Journal:  Semin Cell Dev Biol        ISSN： 1084-9521            Impact factor:   7.727


  10 in total

Review 1.  Fetal environment, epigenetics, and pediatric renal disease.

Authors:  Robert Woroniecki; Anil Bhanudas Gaikwad; Katalin Susztak
Journal:  Pediatr Nephrol       Date:  2010-12-21       Impact factor: 3.714

Review 2.  Epigenetic modifications and human disease.

Authors:  Anna Portela; Manel Esteller
Journal:  Nat Biotechnol       Date:  2010-10       Impact factor: 54.908

Review 3.  Phenotypic impact of genomic structural variation: insights from and for human disease.

Authors:  Joachim Weischenfeldt; Orsolya Symmons; François Spitz; Jan O Korbel
Journal:  Nat Rev Genet       Date:  2013-02       Impact factor: 53.242

Review 4.  X chromosome inactivation in human and mouse pluripotent stem cells.

Authors:  Guoping Fan; Jamie Tran
Journal:  Hum Genet       Date:  2011-06-16       Impact factor: 4.132

Review 5.  Role of tissue-specific AT-rich DNA sequence-binding proteins in lymphocyte differentiation.

Authors:  Takafumi Yokota; Yuzuru Kanakura
Journal:  Int J Hematol       Date:  2014-06-18       Impact factor: 2.490

Review 6.  Role of ATRX in chromatin structure and function: implications for chromosome instability and human disease.

Authors:  Rabindranath De La Fuente; Claudia Baumann; Maria M Viveiros
Journal:  Reproduction       Date:  2011-06-08       Impact factor: 3.906

Review 7.  X chromosome inactivation: recent advances and a look forward.

Authors:  Sharon F Briggs; Renee A Reijo Pera
Journal:  Curr Opin Genet Dev       Date:  2014-10-27       Impact factor: 5.578

Review 8.  Women-specific factors to consider in risk, diagnosis and treatment of cardiovascular disease.

Authors:  Ronée E Harvey; Kirsten E Coffman; Virginia M Miller
Journal:  Womens Health (Lond)       Date:  2015-03

Review 9.  Biological Function of Long Non-coding RNA (LncRNA) Xist.

Authors:  Wenlun Wang; Lu Min; Xinyuan Qiu; Xiaomin Wu; Chuanyang Liu; Jiaxin Ma; Dongyi Zhang; Lingyun Zhu
Journal:  Front Cell Dev Biol       Date:  2021-06-10

Review 10.  Improving clinical outcomes through attention to sex and hormones in research.

Authors:  Michelle M Mielke; Virginia M Miller
Journal:  Nat Rev Endocrinol       Date:  2021-07-27       Impact factor: 47.564
  10 in total

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