Literature DB >> 19815017

Deceptively simple but simply deceptive--Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects.

Jan Gruber1, Li Fang Ng, Suresh Kumar Poovathingal, Barry Halliwell.   

Abstract

The nematode worm Caenorhabditis elegans (C. elegans) is increasingly popular as a model organism for aging studies as well as for testing antioxidants and other compounds for effects on longevity. However, results in the literature are sometimes confusing and contradictory. This review introduces C. elegans as a model organism, discusses aspects that make it attractive for aging and antioxidant research, and addresses some problems and potential artifacts.

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Year:  2009        PMID： 19815017     DOI： 10.1016/j.febslet.2009.09.051

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  44 in total

Review 1.  Pharmacological lifespan extension of invertebrates.

Authors:  Mark Lucanic; Gordon J Lithgow; Silvestre Alavez
Journal:  Ageing Res Rev       Date:  2012-07-06       Impact factor: 10.895

2.  Healthspan Pharmacology.

Authors:  Mahtab Jafari
Journal:  Rejuvenation Res       Date:  2015-11-10       Impact factor: 4.663

3.  Antioxidants can extend lifespan of Brachionus manjavacas (Rotifera), but only in a few combinations.

Authors:  Terry W Snell; Allison M Fields; Rachel K Johnston
Journal:  Biogerontology       Date:  2012-01-24       Impact factor: 4.277

4.  Lifespan and healthspan benefits of exogenous H2S in C. elegans are independent from effects downstream of eat-2 mutation.

Authors:  Li Theng Ng; Li Fang Ng; Richard Ming Yi Tang; Diogo Barardo; Barry Halliwell; Philip Keith Moore; Jan Gruber
Journal:  NPJ Aging Mech Dis       Date:  2020-06-10

5.  The antioxidant paradox: less paradoxical now?

Authors:  Barry Halliwell
Journal:  Br J Clin Pharmacol       Date:  2013-03       Impact factor: 4.335

6.  Lifespan Extension of Caenorhabditis elegans by Butyricicoccus pullicaecorum and Megasphaera elsdenii with Probiotic Potential.

Authors:  Gayeung Kwon; Jiyun Lee; Jong-Ho Koh; Young-Hee Lim
Journal:  Curr Microbiol       Date:  2017-12-08       Impact factor: 2.188

7.  Lactobacillus salivarius strain FDB89 induced longevity in Caenorhabditis elegans by dietary restriction.

Authors:  Yang Zhao; Liang Zhao; Xiaonan Zheng; Tianjiao Fu; Huiyuan Guo; Fazheng Ren
Journal:  J Microbiol       Date:  2013-04-27       Impact factor: 3.422

8.  A simple culture system for long-term imaging of individual C. elegans.

Authors:  William E Pittman; Drew B Sinha; William B Zhang; Holly E Kinser; Zachary Pincus
Journal:  Lab Chip       Date:  2017-11-07       Impact factor: 6.799

9.  Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform.

Authors:  Mandy Koopman; Quentin Peter; Renée I Seinstra; Michele Perni; Michele Vendruscolo; Christopher M Dobson; Tuomas P J Knowles; Ellen A A Nollen
Journal:  Nat Protoc       Date:  2020-05-20       Impact factor: 13.491

10.  Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension.

Authors:  Sebastian Schmeisser; Steffen Priebe; Marco Groth; Shamci Monajembashi; Peter Hemmerich; Reinhard Guthke; Matthias Platzer; Michael Ristow
Journal:  Mol Metab       Date:  2013-02-14       Impact factor: 7.422
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