| Literature DB >> 19810764 |
Gaoxi Jiang1, Jian Chen, Jie-Sheng Huang, Chi-Ming Che.
Abstract
A variety of secondary benzylic amines were oxidized to imines in 90% to >99% yields by singlet oxygen generated from oxygen and a porphyrin photosensitizer. On the basis of these reactions, a protocol was developed for oxidative Ugi-type reactions with singlet oxygen as the oxidant. This protocol has been used to synthesize C1- and N-functionalized benzylic amines in up to 96% yields.Entities:
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Year: 2009 PMID： 19810764 DOI： 10.1021/ol9018166
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005