Literature DB >> 19810078

C5-functionalized LNA: unparalleled hybridization properties and enzymatic stability.

Michael E Østergaard1, Pawan Kumar, Bharat Baral, Daniel J Raible, T Santhosh Kumar, Brooke A Anderson, Dale C Guenther, Lee Deobald, Andrzej J Paszczynski, Pawan K Sharma, Patrick J Hrdlicka.   

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Year:  2009        PMID: 19810078     DOI: 10.1002/cbic.200900500

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


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  5 in total

1.  Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA.

Authors:  Sujay P Sau; Pawan Kumar; Brooke A Anderson; Michael E Østergaard; Lee Deobald; Andrzej Paszczynski; Pawan K Sharma; Patrick J Hrdlicka
Journal:  Chem Commun (Camb)       Date:  2009-10-12       Impact factor: 6.222

Review 2.  Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): tools for fundamental research, diagnostics, and nanotechnology.

Authors:  Michael E Østergaard; Patrick J Hrdlicka
Journal:  Chem Soc Rev       Date:  2011-04-13       Impact factor: 54.564

3.  C5-alkynyl-functionalized α-L-LNA: synthesis, thermal denaturation experiments and enzymatic stability.

Authors:  Pawan Kumar; Bharat Baral; Brooke A Anderson; Dale C Guenther; Michael E Østergaard; Pawan K Sharma; Patrick J Hrdlicka
Journal:  J Org Chem       Date:  2014-05-13       Impact factor: 4.354

4.  Fluorescent intercalator displacement replacement (FIDR) assay: determination of relative thermodynamic and kinetic parameters in triplex formation--a case study using triplex-forming LNAs.

Authors:  Sujay P Sau; Pawan Kumar; Pawan K Sharma; Patrick J Hrdlicka
Journal:  Nucleic Acids Res       Date:  2012-08-01       Impact factor: 16.971

5.  Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid).

Authors:  Pawan Kumar; Michael E Østergaard; Bharat Baral; Brooke A Anderson; Dale C Guenther; Mamta Kaura; Daniel J Raible; Pawan K Sharma; Patrick J Hrdlicka
Journal:  J Org Chem       Date:  2014-05-13       Impact factor: 4.354

  5 in total

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